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Children's Health Exposure Analysis Resource
Last uploaded:
September 10, 2019
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| Id | http://purl.obolibrary.org/obo/CL_0000669
http://purl.obolibrary.org/obo/CL_0000669
|
|---|---|
| Preferred Name | pericyte |
| Definitions |
An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells.
Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.
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| Synonyms |
adventitial cell
pericyte cell
adventitial reticular cell
cell of Rouget
pericyte of Rouget
ARC
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A. |
|---|---|
| alternative label |
adventitial cell
pericyte cell
adventitial reticular cell
cell of Rouget
pericyte of Rouget
ARC
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|
| label |
pericyte
|
| comment |
Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.
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| prefLabel |
pericyte
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| database_cross_reference |
BTO:0002441
FMA:63174
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| in_subset | |
| has_related_synonym |
adventitial cell
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| prefixIRI |
CL:0000669
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| textual definition |
An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells.
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| present_in_taxon | |
| subClassOf | |
| type | |
| has_exact_synonym |
pericyte cell
adventitial reticular cell
cell of Rouget
pericyte of Rouget
ARC
|
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