Children's Health Exposure Analysis Resource

Last uploaded: September 10, 2019
Id http://purl.obolibrary.org/obo/CL_0000127
http://purl.obolibrary.org/obo/CL_0000127
Preferred Name

astrocyte

Definitions
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive.
Synonyms
astrocytic glia
Type http://www.w3.org/2002/07/owl#Class
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