Children's Health Exposure Analysis Resource

Last uploaded: September 10, 2019
Preferred Name

Electrospray Ionization Mass Spectrometry

Synonyms
Definitions

Mass spectrometry using ESI is called electrospray ionization mass spectrometry (ESI-MS) or, less commonly, electrospray mass spectrometry (ES-MS). ESI is a so-called 'soft ionization' technique, since there is very little fragmentation. This can be advantageous in the sense that the molecular ion (or more accurately a pseudo molecular ion) is always observed, however very little structural information can be gained from the simple mass spectrum obtained. This disadvantage can be overcome by coupling ESI with tandem mass spectrometry (ESI-MS/MS). Another important advantage of ESI is that solution-phase information can be retained into the gas-phase.

ID

http://hadatac.org/ont/chear#ElectrosprayIonizationMassSpectrometry

definition

Mass spectrometry using ESI is called electrospray ionization mass spectrometry (ESI-MS) or, less commonly, electrospray mass spectrometry (ES-MS). ESI is a so-called 'soft ionization' technique, since there is very little fragmentation. This can be advantageous in the sense that the molecular ion (or more accurately a pseudo molecular ion) is always observed, however very little structural information can be gained from the simple mass spectrum obtained. This disadvantage can be overcome by coupling ESI with tandem mass spectrometry (ESI-MS/MS). Another important advantage of ESI is that solution-phase information can be retained into the gas-phase.

label

Electrospray Ionization Mass Spectrometry

prefLabel

Electrospray Ionization Mass Spectrometry

wasApprovedBy

chear-kb:PER-Jim-McCusker

subClassOf

http://hadatac.org/ont/hasco/MassSpectrometry

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