loading...| Preferred Name | Toxic epidermal necrolysis | |
| Synonyms |
TEN Lyell syndrome Lyell's Syndrome |
|
| Definitions |
A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes OR A systemic, serious, and life-threatening disorder characterized by erythematous and necrotic lesions in the skin and mucous membranes that are associated with bullous detachment of the epidermis. The epidermal and mucous membranes detachment leads to sepsis and may be fatal. The lesions appear throughout the body and occupy more than 30% of the body surfaces. It is a hypersensitivity reaction usually caused by drugs (e.g., sulfonamides, nonsteroidal anti-inflammatory drugs, anticonvulsants, and antiretroviral drugs). |
|
| ID |
http://purl.obolibrary.org/obo/CCTO_001083 |
|
| database_cross_reference |
UMLS:C0014518 NCI:CTCAE:10044223 UMLS:C0205456 NCIT:C79777 |
|
| definition |
A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes OR A systemic, serious, and life-threatening disorder characterized by erythematous and necrotic lesions in the skin and mucous membranes that are associated with bullous detachment of the epidermis. The epidermal and mucous membranes detachment leads to sepsis and may be fatal. The lesions appear throughout the body and occupy more than 30% of the body surfaces. It is a hypersensitivity reaction usually caused by drugs (e.g., sulfonamides, nonsteroidal anti-inflammatory drugs, anticonvulsants, and antiretroviral drugs). |
|
| has_exact_synonym |
TEN Lyell syndrome Lyell's Syndrome |
|
| has_obo_namespace |
cancer_care_treatment_outcome |
|
| id |
CCTO:001083 |
|
| label |
Toxic epidermal necrolysis |
|
| notation |
CCTO:001083 |
|
| prefLabel |
Toxic epidermal necrolysis |
|
| schema |
CCTO:001083(time_t t0) = EVENT_STATE(CCTO:001083, t0) |
|
| treeView | ||
| XSTOO_rule |
CCTO:001083 implies CCTO:000049 CCTO:001083 implies CCTO:001128 |
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| subClassOf | ||
| is_assessed_by |