Preferred Name

Myelodysplastic syndrome
Synonyms

myelodysplastic syndromes

MDS

Myelodysplastic syndrome, NOS

Myelodysplastic syndrome/neoplasm

Dysmyelopoietic syndrome

NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology

Myelodysplastic neoplasm

NCI CTEP Simple Disease Classification Myelodysplastic Syndrome Sub-Category Terminology

Myelodysplasia

Oligoblastic leukemia

Preleukemia

Smoldering leukemia

Hematopoeitic - Myelodysplastic Syndrome (MDS)

Definitions

Myelodysplastic Syndrome is an NCI Cancer Therapeutic Evaluation Program (CTEP) Simplified Disease Classification (SDC) category used to organize cancer-related disease coding that harmonizes with and supports reporting based on the global standard Medical Dictionary for Drug Regulatory Reporting (MedDRA) terminology OR A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) OR A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow.

ID

http://purl.obolibrary.org/obo/CCTO_000843

database_cross_reference

UMLS:C0002894

UMLS:C3463824

UMLS:C0033027

NCIT:C3247

UMLS:C0026986

NCIT:C103128

UMLS:C0026985

NCI:CTCAE:10028533

UMLS:C2698684

UMLS:C3538995

definition

Myelodysplastic Syndrome is an NCI Cancer Therapeutic Evaluation Program (CTEP) Simplified Disease Classification (SDC) category used to organize cancer-related disease coding that harmonizes with and supports reporting based on the global standard Medical Dictionary for Drug Regulatory Reporting (MedDRA) terminology OR A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) OR A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow.

has_exact_synonym

myelodysplastic syndromes

MDS

Myelodysplastic syndrome, NOS

Myelodysplastic syndrome/neoplasm

Dysmyelopoietic syndrome

NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology

Myelodysplastic neoplasm

NCI CTEP Simple Disease Classification Myelodysplastic Syndrome Sub-Category Terminology

Myelodysplasia

Oligoblastic leukemia

Preleukemia

Smoldering leukemia

Hematopoeitic - Myelodysplastic Syndrome (MDS)

has_obo_namespace

cancer_care_treatment_outcome

id

CCTO:000843

label

Myelodysplastic syndrome

notation

CCTO:000843

prefLabel

Myelodysplastic syndrome

schema

CCTO:000843(time_t t0) = EVENT_STATE(CCTO:000843, t0)

treeView

http://purl.obolibrary.org/obo/CCTO_001122

http://purl.obolibrary.org/obo/CCTO_000049

XSTOO_rule

CCTO:000843 implies CCTO:001122

CCTO:000843 implies CCTO:000049

subClassOf

http://purl.obolibrary.org/obo/CCTO_001122

http://purl.obolibrary.org/obo/CCTO_000049

is_assessed_by

http://purl.obolibrary.org/obo/CCTO_000347

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Delete Mapping To Ontology Source
http://ncicb.nci.nih.gov/xml/owl/EVS/ctcae5.owl#C143690 CTCAE LOOM
http://nanbyodata.jp/ontology/NANDO_2200019 NANDO LOOM
http://www.limics.org/hrdo/rdfns#sgn_id_51090 HRDO LOOM
http://www.ebi.ac.uk/efo/EFO_0000198 CCONT LOOM
http://www.ebi.ac.uk/efo/EFO_0000198 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_0000198 EFO LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU024110 OMIM LOOM
http://purl.bioontology.org/ontology/MEDDRA/10028533 MEDDRA LOOM
http://purl.bioontology.org/ontology/ICPC2P/B75008 ICPC2P LOOM
http://purl.bioontology.org/ontology/RCD/Xa0SY RCD LOOM
http://purl.bioontology.org/ontology/SNMI/M-99800 SNMI LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Myelodysplastic_Syndrome CSEO LOOM
http://identifiers.org/omim/614286 REXO LOOM
http://identifiers.org/omim/614286 GEXO LOOM
http://identifiers.org/omim/614286 RETO LOOM
http://purl.obolibrary.org/obo/DOID_0050908 DTO LOOM
http://purl.obolibrary.org/obo/DOID_0050908 DOID LOOM
http://purl.obolibrary.org/obo/DOID_0050908 HHEAR LOOM
http://purl.obolibrary.org/obo/DOID_0050908 DDSS LOOM
http://purl.obolibrary.org/obo/DOID_0050908 NIFSTD LOOM
http://purl.obolibrary.org/obo/DOID_0050908 MIDO LOOM
http://purl.obolibrary.org/obo/DOID_0050908 FNS-H LOOM
rgo:22743 GAMUTS LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3247 NCIT LOOM
http://purl.obolibrary.org/obo/OMIM_614286 CCO LOOM
http://www.orpha.net/ORDO/Orphanet_52688 ORDO LOOM
http://nanbyodata.jp/ontology/NANDO_2100003 NANDO LOOM
http://purl.bioontology.org/ontology/OMIM/614286 OMIM LOOM
http://purl.jp/bio/4/id/200906062683367267 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LA26796-5 LOINC LOOM
http://purl.obolibrary.org/obo/MONDO_0018881 MONDO LOOM
http://purl.obolibrary.org/obo/MONDO_0018881 DOVES LOOM
http://purl.obolibrary.org/obo/NCIT_C3247 BERO LOOM