Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Synonyms

thyroid

glandula thyroidea

Definitions

A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO].

ID

http://purl.obolibrary.org/obo/UBERON_0002046

database_cross_reference

EHDAA2:0002028

MESH:D013961

NCIT:C12400

VHOG:0000418

MIAA:0000081

BTO:0001379

Wikipedia:Thyroid

EMAPA:17068

MAT:0000081

CALOHA:TS-1047

EFO:0000861

AAO:0010544

XAO:0000162

SCTID:181117000

galen:ThyroidGland

UMLS:C0040132

EHDAA:2148

EHDAA:2975

EV:0100133

FMA:9603

GAID:465

MA:0000129

definition

A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO].

depiction

http://upload.wikimedia.org/wikipedia/commons/c/c6/Illu_endocrine_system.jpg

http://upload.wikimedia.org/wikipedia/commons/a/a3/Illu_thyroid_parathyroid.jpg

external_definition

Either of paired structures located in the throat which develop from the ventral wall of the pharynx and excretes hormones involved in the morphological and functional changes during metamorphosis as well as influencing other tissues.[AAO]

has_exact_synonym

thyroid

has_obo_namespace

uberon

has_related_synonym

glandula thyroidea

homology_notes

(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (2) a groove in the pharyngeal floor known as the endostyle, or a thyroid gland derived from part of the endostyle (...).[well established][VHOG]

id

UBERON:0002046

in_subset

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#organ_slim

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

thyroid gland

notation

UBERON:0002046

part_of

http://purl.obolibrary.org/obo/UBERON_0000949

taxon_notes

In tetrapods, the thyroid is always found somewhere in the neck region. In most tetrapod species, there are two paired thyroid glands - that is, the right and left lobes are not joined together. However, there is only ever a single thyroid gland in most mammals, and the shape found in humans is common to many other species

In fish, it is usually located below the gills and is not always divided into distinct lobes. However, in some teleosts, patches of thyroid tissue are found elsewhere in the body, associated with the kidneys, spleen, heart, or eyes

In larval lampreys, the thyroid originates as an exocrine gland, secreting its hormones into the gut, and associated with the larva's filter-feeding apparatus. In the adult lamprey, the gland separates from the gut, and becomes endocrine, but this path of development may reflect the evolutionary origin of the thyroid. For instance, the closest living relatives of vertebrates, the tunicates and Amphioxus, have a structure very similar to that of larval lampreys, and this also secretes iodine-containing compounds (albeit not thyroxine)

treeView

http://purl.obolibrary.org/obo/UBERON_0000949

subClassOf

http://purl.obolibrary.org/obo/UBERON_0002368

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