Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Synonyms

anterior uvea

irides

irises

Definitions

The adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye.

ID

http://purl.obolibrary.org/obo/UBERON_0001769

database_cross_reference

ZFA:0001238

MESH:D007498

BTO:0000653

CALOHA:TS-0491

Wikipedia:Iris_(anatomy)

XAO:0000185

AAO:0010347

UMLS:C0022077

EFO:0004245

VHOG:0000101

TAO:0001238

NCIT:C12737

SCTID:181164000

EMAPA:19154

EV:0100345

FMA:58235

GAID:917

MA:0000273

definition

The adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye.

external_definition

The opaque muscular contractile diaphragm suspended in the aqueous humour in front of the lens of the eye. The organ is perforated by the pupil and continues peripherally with the ciliary body. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]

has_obo_namespace

uberon

has_related_synonym

anterior uvea

irides

irises

has_relational_adjective

iridial

homology_notes

The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]

id

UBERON:0001769

in_subset

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

iris

notation

UBERON:0001769

RO_0002175

http://purl.obolibrary.org/obo/NCBITaxon_9606

taxon_notes

The avian iris and ciliary body undergoes a transition from smooth-to-striated muscle during embryonic development [DOI:dx.doi.org/10.1006/dbio.1998.9019]

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000061

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