loading...| Preferred Name |
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| Synonyms |
Henle's loop ansa nephroni Henle loop |
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| Definitions |
The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine. |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0001288 |
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| database_cross_reference |
Wikipedia:Loop_of_Henle SCTID:361335009 VHOG:0001270 EMAPA:19280 UMLS:C0023986 MESH:D008138 BTO:0004608 NCIT:C33006 EV:0100390 FMA:17698 GAID:437 MA:0001675 |
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| definition |
The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine. |
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| depiction |
http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png |
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| dubious_for_taxon | ||
| editor note |
the definitions of some kidney parts (e.g. proximal straight tubule) refer to Henle's loop, even in species where this may not be present. Requires review. |
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| external_definition |
A highly specialized segment of the mammalian kidney tubules, that dips into the medulla. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Grande_L, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF, p.648, see_Liem_KF][VHOG] |
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| has_exact_synonym |
Henle's loop ansa nephroni Henle loop |
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| has_obo_namespace |
uberon |
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| id |
UBERON:0001288 |
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| in_subset | ||
| label |
loop of Henle |
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| notation |
UBERON:0001288 |
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| part_of |
http://purl.obolibrary.org/obo/UBERON_0001231 |
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| RO_0002175 | ||
| taxon_notes |
The structure differs considerably between species; there is a definite physical loop of Henle in the mammalian and avian renal systems but this seems to be absent in Xenopus. However, homologs of some, but not all, molecular markers (e.g. cldn8 and clcnk) of the mammalian loop of Henle were found to be present in the pronephros of the frog larva . |
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| treeView |
http://purl.obolibrary.org/obo/UBERON_0001231 |
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| UBPROP_0000009 |
The loop of Henle plays an important role in creating a concentration gradient in the medulla of the kidney. It is involved in reabsorption of filtered water and ions including sodium, potassium and calcium, and independently regulates both the volume and osmolarity of body fluids. |
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| subClassOf |