Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

esophagus

Synonyms

gullet

œsophagus

oesophagus

Entire esophagus

Definitions

Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993). AO notes: esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995)

ID

http://purl.obolibrary.org/obo/UBERON_0001043

comment

AO notes: esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995)

database_cross_reference

NCIT:C12389

Wikipedia:Esophagus

NCIt:C12389

CALOHA:TS-0700

ANISEED:1235301

BTO:0000959

UMLS:C0014876

EMAPA:16833

EV:0100069

OpenCyc:Mx4rvVj9Q5wpEbGdrcN5Y29ycA

XAO:0000127

GAID:291

galen:Esophagus

MAT:0000048

SNOMEDCT:181245004

MESH:A03.365

VHOG:0000450

FMA:7131

http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg

AAO:0000145

MA:0000352

ZFA:0000204

EHDAA:2937

EMAPA:18860

EHDAA2:0001285

MIAA:0000048

MSH:D004947

TAO:0000204

EFO:0000835

http://linkedlifedata.com/resource/umls/id/C0014876

http://en.wikipedia.org/wiki/Esophagus

http://www.snomedbrowser.com/Codes/Details/181245004

definition

Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993).

depicted_by

http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg

develops_from

http://purl.obolibrary.org/obo/UBERON_0000925

http://purl.obolibrary.org/obo/UBERON_0001007

external_definition

Anterior end of the alimentary canal lined with smooth muscle. Bounded anteriorly by a constriction in the pharynx. Bounded posteriorly by and increase in circular and/or longitudinal smooth muscle associated with the stomach.[AAO]

external_ontology_notes

esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995)

has_exact_synonym

gullet

œsophagus

oesophagus

Entire esophagus

has_obo_namespace

uberon

has_relational_adjective

esophageal

homologous_in

http://purl.obolibrary.org/obo/NCBITaxon_7742

homology_notes

The few structural specializations in (adult lampreys) pharynx include complex valves on the external gill openings that direct the tidal flow, and the division of the ancestral pharynx into an oesophagus and a respiratory pharynx.[well established][VHOG]

id

UBERON:0001043

in_subset

http://purl.obolibrary.org/obo/uberon#major_organ

http://purl.obolibrary.org/obo/uberon#efo_slim

http://purl.obolibrary.org/obo/uberon/core#major_organ

http://purl.obolibrary.org/obo/uberon#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#organ_slim

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon#organ_slim

label

esophagus

notation

UBERON:0001043

part_of

http://purl.obolibrary.org/obo/UBERON_0001007

prefLabel

esophagus

treeView

http://purl.obolibrary.org/obo/UBERON_0000925

http://purl.obolibrary.org/obo/UBERON_0001007

subClassOf

http://purl.obolibrary.org/obo/UBERON_0004921

http://purl.obolibrary.org/obo/UBERON_0005178

http://purl.obolibrary.org/obo/UBERON_0013765

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http://purl.bioontology.org/ontology/LNC/MTHU011962 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0545823 OCHV LOOM
http://purl.obolibrary.org/obo/TAO_0000204 TAO LOOM
http://radlex.org/RID/RID95 RADLEX LOOM
http://www.co-ode.org/ontologies/galen#Esophagus GALEN LOOM
http://purl.obolibrary.org/obo/MooccuA_0000621 MOOCCUADO LOOM
http://localhost/plosthes.2017-1#10298 PLOSTHES LOOM
http://purl.obolibrary.org/obo/PLANA_0000062 PLANP LOOM
http://purl.obolibrary.org/obo/PLANA_0000062 PLANA LOOM
http://www.semanticweb.org/ontologies/2012/11/abnormalities.owl#phenodb:1034 IFAR LOOM
http://purl.obolibrary.org/obo/PhmammA_0000621 PHMAMMADO LOOM
http://purl.obolibrary.org/obo/PhfumiA_0000621 PHFUMIADO LOOM
http://purl.obolibrary.org/obo/MFMO_0000049 MFMO LOOM
http://purl.obolibrary.org/obo/SPD_0000629 SPD LOOM
http://purl.obolibrary.org/obo/SPD_0000629 SPD LOOM
http://purl.org/obo/owlapi/fma#FMA_7131 BIOMODELS LOOM
http://purl.obolibrary.org/obo/BSA_0000074 BSAO LOOM
http://purl.obolibrary.org/obo/BTO_0000959 BTO LOOM
http://purl.obolibrary.org/obo/BTO_0000959 DTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A03.556.875.500 RH-MESH LOOM
http://purl.jp/bio/11/meo/MEO_0000789 MEO LOOM
http://bioportal.bioontology.org/ontologies/FISHO#FISHO_0000351 FISHO LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 UBERON LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 UBERON SAME_URI
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http://purl.obolibrary.org/obo/UBERON_0001043 DTO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 TXPO LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 TXPO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 CEPH LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 CEPH SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 GO-PLUS LOOM
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http://purl.obolibrary.org/obo/UBERON_0001043 OBIB LOOM
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http://purl.obolibrary.org/obo/UBERON_0001043 CHEAR LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 CHEAR SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 CLO LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 CLO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 UBERON LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 UBERON SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 TXPO LOOM
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http://purl.obolibrary.org/obo/UBERON_0001043 ENVO SAME_URI
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http://purl.obolibrary.org/obo/UBERON_0001043 GENEPIO LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 GENEPIO SAME_URI
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http://purl.obolibrary.org/obo/UBERON_0001043 TXPO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 EFO LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 EFO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 BAO LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 BAO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 GO-PLUS LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 UPHENO LOOM
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http://purl.obolibrary.org/obo/UBERON_0001043 TXPO LOOM
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http://purl.obolibrary.org/obo/UBERON_0001043 UBERON LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 UBERON SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 UBERON LOOM
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http://purl.obolibrary.org/obo/UBERON_0001043 OCVDAE LOOM
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http://purl.obolibrary.org/obo/UBERON_0001043 TXPO LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 TXPO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 NIFSTD LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 CL LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 CL SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 OBA LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 OBA SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 OAE LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 OAE SAME_URI
http://www.projecthalo.com/aura#Esophagus AURA LOOM
http://purl.bioontology.org/ontology/MESH/D004947 MESH LOOM
urn:absolute:RadiationOncologyStructuresOntology#Esophagus ROS LOOM
http://purl.bioontology.org/ontology/LNC/LP199925-1 LOINC LOOM
http://purl.obolibrary.org/obo/EMAPA_16833 EMAPA LOOM
http://purl.obolibrary.org/obo/XAO_0000127 XAO LOOM
http://purl.obolibrary.org/obo/XAO_0000127 XPO LOOM
http://purl.obolibrary.org/obo/XAO_0000127 XPO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#4665 OCHV LOOM
http://purl.obolibrary.org/obo/MA_0000352 MA LOOM
http://purl.obolibrary.org/obo/MooculA_0000621 MOOCULADO LOOM
http://purl.obolibrary.org/obo/ZFA_0000204 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0000204 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0000204 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0000204 UPHENO LOOM
http://purl.obolibrary.org/obo/ZFA_0000204 ZP LOOM
http://purl.obolibrary.org/obo/ZFA_0000204 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0000204 ZFA LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12389 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12389 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Esophagus SYN LOOM
http://purl.obolibrary.org/obo/CiinteA_0000621 CIINTEADO LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Esophagus APAONTO LOOM
http://www.bioontology.org/pma.owl#PMA_688 PMA LOOM
http://purl.bioontology.org/ontology/LNC/LP29941-9 LOINC LOOM
https://bioportal.bioontology.org/ontologies/ICD-O-3-T/C15 ICD-O-3-T LOOM
http://scai.fraunhofer.de/CSEO#Esophagus CSEO LOOM
http://purl.obolibrary.org/obo/HaauraA_0000621 HAAURAADO LOOM
http://purl.bioontology.org/ontology/CSP/1250-0527 CRISP LOOM
http://www.semanticweb.org/pallabi.d/ontologies/2014/2/untitled-ontology-11#Esophagus MCCL LOOM
http://purl.obolibrary.org/obo/FBbt_00005381 FB-BT LOOM
http://purl.obolibrary.org/obo/FBbt_00005381 FB-BT LOOM
http://purl.org/sig/ont/fma/fma7131 FMA LOOM
http://purl.org/sig/ont/fma/fma7131 ROO LOOM
http://purl.bioontology.org/ontology/LNC/LA4018-3 LOINC LOOM
http://www.semanticweb.org/david/ontologies/2013/0/pathLex.owl#1.3.6.1.4.1.19376.1.8.2.1.761 PATHLEX LOOM
http://purl.obolibrary.org/obo/CisaviA_0000621 CISAVIADO LOOM
http://doe-generated-ontology.com/OntoPneumo#Oesophage ONTOPNEUMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004947 RH-MESH LOOM
http://purl.obolibrary.org/obo/MoocciA_0000621 MOOCCIADO LOOM
http://purl.bioontology.org/ontology/MTHMST/MT010002 MSTDE-FRE LOOM
http://purl.bioontology.org/ontology/MTHMST/MT010002 MSTDE LOOM
http://sig.uw.edu/fma#Esophagus HUPSON LOOM
http://purl.obolibrary.org/obo/MFO_0003000 MFO LOOM
http://www.semanticweb.org/ontologies/2010/10/BPO.owl#esophagus BHO LOOM
http://purl.obolibrary.org/obo/HaroreA_0000621 HAROREADO LOOM
http://purl.jp/bio/4/id/200906017837530284 IOBC LOOM
http://purl.obolibrary.org/obo/AAO_0000145 AAO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0014876 OCHV LOOM