loading...| Preferred Name |
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| Synonyms |
systema nervosum centrale CNS neuraxis cerebrospinal axis |
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| Definitions |
The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0001017 |
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| database_cross_reference |
NCIT:C12438 VHOG:0000293 EMAPA:16754 BIRNLEX:1099 EHDAA2:0000225 UMLS:C0927232 EMAPA:16470 FBbt:00005094 AAO:0000090 BILA:0000080 XAO:0000215 SCTID:278199004 ZFA:0000012 neuronames:854 CALOHA:TS-0150 EFO:0000908 BTO:0000227 Wikipedia:Central_nervous_system MAT:0000457 TAO:0000012 MESH:D002490 BAMS:CNS EHDAA:828 EV:0100163 FMA:55675 GAID:570 MA:0000167 |
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| definition |
The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. |
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| external_definition |
Part of the nervous system which includes the brain and spinal cord.[AAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). The brain and spinal cord. Kimmel et al, 1995.[TAO] |
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| has_exact_synonym |
systema nervosum centrale CNS |
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| has_narrow_synonym |
cerebrospinal axis |
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| has_obo_namespace |
uberon |
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| has_related_synonym |
neuraxis |
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| homology_notes |
(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG] |
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| id |
UBERON:0001017 |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/uberon/core#efo_slim http://purl.obolibrary.org/obo/uberon/core#cumbo http://purl.obolibrary.org/obo/uberon/core#vertebrate_core |
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| label |
central nervous system |
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| never_in_taxon | ||
| notation |
UBERON:0001017 |
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| part_of | ||
| RO_0002175 | ||
| treeView | ||
| subClassOf |