Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Synonyms

retina of camera-type eye

inner layer of eyeball

tunica interna of eyeball

Netzhaut

retinas

Definitions

Currently this class encompasses only verteberate AOs but could in theory also include cephalopod - we may want to make a more specific class for vertebrate retina. note that this class excludes ommatidial retinas, as the retina must be part of an eyeball. Use the parent class photoreceptor array / light-sensitive tissue for arthropods The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.

ID

http://purl.obolibrary.org/obo/UBERON_0000966

comment

Currently this class encompasses only verteberate AOs but could in theory also include cephalopod - we may want to make a more specific class for vertebrate retina. note that this class excludes ommatidial retinas, as the retina must be part of an eyeball. Use the parent class photoreceptor array / light-sensitive tissue for arthropods

database_cross_reference

BTO:0001175

SCTID:181171005

XAO:0000009

BIRNLEX:1153

neuronames:1862

UMLS:C1278894

ZFA:0000152

EMAPA:17168

NCIT:C12343

MAT:0000142

Wikipedia:Retina

VHOG:0000229

MESH:D012160

EHDAA2:0001627

AAO:0010352

TAO:0000152

EFO:0000832

UMLS:C0035298

MBA:304325711

NIFSTD_RETIRED:birnlex_1156

CALOHA:TS-0865

MIAA:0000142

BAMS:R

EHDAA:4757

EV:0100348

FMA:58301

GAID:755

MA:0000276

definition

The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.

depiction

http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png

external_definition

The portion of the eye developing from the optic primordium and including the neural retina and the retinal pigment layer. Kimmel et al, 1995.[TAO]

has_exact_synonym

retina of camera-type eye

inner layer of eyeball

tunica interna of eyeball

has_obo_namespace

uberon

has_related_synonym

Netzhaut

retinas

has_relational_adjective

retinal

homology_notes

The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]

id

UBERON:0000966

in_subset

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

retina

never_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_6656

notation

UBERON:0000966

part_of

http://purl.obolibrary.org/obo/UBERON_0000970

http://purl.obolibrary.org/obo/UBERON_0001016

RO_0002175

http://purl.obolibrary.org/obo/NCBITaxon_9606

treeView

http://purl.obolibrary.org/obo/UBERON_0000970

http://purl.obolibrary.org/obo/UBERON_0001016

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000061

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