loading...| Preferred Name | Morvan syndrome | |
| Synonyms |
Morvan's fibrillary chorea Morvan's syndrome limbic encephalitis-neuromyotonia-hyperhidrosis-polyneuropathy syndrome Morvan syndrome MFC MoS |
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| Definitions |
Morvan syndrome is a rare, life-threatening, acquired neurologic disease characterized by neuromyotonia, dysautonomia and encephalopathy with severe insomnia. Signs involving central (e.g. hallucinations, confusion, amnesia, myoclonus), autonomic (e.g. variations in blood pressure, hyperhidrosis) and peripheral (e.g. painful cramps, myokymia) hyperactivity, as well as systemic manifestations (such as weight loss, pruritus, fever), are reported. Thymoma is present in some cases. Morvan syndrome is a rare autoimmune/paraneoplastic disorder involving antibodies to the voltage-gated potassium channel complex. It is defined by subacute encephalopathy, neuromuscular hyperexcitability, dysautonomia, and sleep disturbance. [PMID:27224435] |
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| ID |
http://www.ebi.ac.uk/efo/EFO_1001897 |
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| database_cross_reference |
Orphanet:83467 MONDO:0008718 ORDO:Orphanet_83467 MedDRA:10075006 SCTID:763803004 MEDGEN:1632829 UMLS:C3854373 Wikipedia:Morvan%27s_syndrome GARD:9766 |
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| definition |
Morvan syndrome is a rare, life-threatening, acquired neurologic disease characterized by neuromyotonia, dysautonomia and encephalopathy with severe insomnia. Signs involving central (e.g. hallucinations, confusion, amnesia, myoclonus), autonomic (e.g. variations in blood pressure, hyperhidrosis) and peripheral (e.g. painful cramps, myokymia) hyperactivity, as well as systemic manifestations (such as weight loss, pruritus, fever), are reported. Thymoma is present in some cases. Morvan syndrome is a rare autoimmune/paraneoplastic disorder involving antibodies to the voltage-gated potassium channel complex. It is defined by subacute encephalopathy, neuromuscular hyperexcitability, dysautonomia, and sleep disturbance. [PMID:27224435] |
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| has_exact_synonym |
Morvan's fibrillary chorea Morvan's syndrome limbic encephalitis-neuromyotonia-hyperhidrosis-polyneuropathy syndrome Morvan syndrome MFC MoS |
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| id |
EFO:1001897 |
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| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-base#nord_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_disorder |
|
| label |
Morvan syndrome |
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| notation |
EFO:1001897 |
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| preferred label |
Morvan syndrome |
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| prefLabel |
Morvan syndrome |
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| skos_exactMatch |
http://purl.obolibrary.org/obo/Orphanet_83467 http://identifiers.org/medgen/1632829 http://identifiers.org/snomedct/763803004 |
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| term editor |
Gautier Koscielny |
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| subClassOf |