loading...| Preferred Name | kuru | |
| Synonyms |
kuru encephalopathy Kuru kuru |
|
| Definitions |
A prion disease found exclusively among the Fore linguistic group natives of the highlands of new guinea. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773) A prion disease found exclusively among the Fore linguistic group natives of the highlands of NEW GUINEA. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773) |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_1001008 |
|
| database_cross_reference |
MEDGEN:9653 ICD10:A81.81 SCTID:86188000 ICD10CM:A81.81 MESH:D007729 Orphanet:454745 UMLS:C0022802 MeSH:D007729 MedDRA:10023497 SNOMEDCT:86188000 icd11.foundation:553889510 MONDO:0006825 DOID:648 GARD:7617 ICD9:046.0 |
|
| definition |
A prion disease found exclusively among the Fore linguistic group natives of the highlands of new guinea. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773) A prion disease found exclusively among the Fore linguistic group natives of the highlands of NEW GUINEA. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773) |
|
| disease arises from feature | ||
| has_exact_synonym |
kuru encephalopathy Kuru kuru |
|
| id |
EFO:1001008 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-base#nord_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_disorder |
|
| label |
kuru |
|
| notation |
EFO:1001008 |
|
| preferred label |
kuru |
|
| prefLabel |
kuru |
|
| see also | ||
| skos_closeMatch | ||
| skos_exactMatch |
http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/553889510 http://purl.obolibrary.org/obo/Orphanet_454745 http://identifiers.org/medgen/9653 http://linkedlifedata.com/resource/umls/id/C0022802 http://identifiers.org/mesh/D007729 http://purl.obolibrary.org/obo/EFO_1001008 http://purl.bioontology.org/ontology/ICD10CM/A81.81 |
|
| term editor |
Sirarat Sarntivijai |
|
| subClassOf |
http://www.ebi.ac.uk/efo/EFO_0004280 |