loading...| Preferred Name | Granular Cell Tumor | |
| Synonyms |
granular cell tumour NOS (morphologic abnormality) neoplasm of granular cell granular cell tumor NOS (morphologic abnormality) giant granulocellular Abrikosov's tumor Abrikosoff's granulous cell tumour malignant variant of Abrikosov's tumour Abrikosoff's tumor malignant variant of Abrikosov's tumor Abrikosoff's tumour Abrikosoff's granulous cell tumor Abrikosov's tumour giant granulocellular Abrikosov's tumour Abrikosov’s tumour Abrikosov’s tumor Abrikosov's tumor GCT Abrikossoff's tumor granular cell schwannoma Abrikossoff tumor granular cell tumour (morphologic abnormality) granular cell nerve sheath tumour Abrikossoff tumour granular cell nerve sheath tumor Abrikossoff's tumour granular cell tumor granular cell tumor (morphologic abnormality) granular cell neoplasm granular cell myoblastoma |
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| Definitions |
An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast. Editor note: MESH considers this a myoblastoma but we go with NCIT which states nerve sheath origin, consistent with GARD definition; also check ONCOTREE placement |
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| ID |
http://www.ebi.ac.uk/efo/EFO_1000284 |
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| comment |
Editor note: MESH considers this a myoblastoma but we go with NCIT which states nerve sheath origin, consistent with GARD definition; also check ONCOTREE placement |
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| closeMatch | ||
| database_cross_reference |
GARD:0009618 SCTID:404035005 EFO:1000284 MONDO:0006235 MESH:C535558 MEDGEN:88345 ICDO:9580/0 MESH:D016586 UMLS:C0085167 ONCOTREE:GCT DOID:2411 GARD:9618 ICD9:215.9 NCIT:C3474 |
|
| definition |
An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast. |
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| exactMatch |
http://identifiers.org/mesh/C535558 http://purl.obolibrary.org/obo/NCIT_C3474 http://identifiers.org/mesh/D016586 http://purl.obolibrary.org/obo/DOID_2411 |
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| has_exact_synonym |
Abrikossoff's tumor granular cell schwannoma Abrikossoff tumor granular cell tumour (morphologic abnormality) granular cell nerve sheath tumour Abrikossoff tumour granular cell nerve sheath tumor Abrikossoff's tumour granular cell tumor granular cell tumor (morphologic abnormality) granular cell neoplasm granular cell myoblastoma |
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| has_narrow_synonym |
granular cell tumour NOS (morphologic abnormality) neoplasm of granular cell granular cell tumor NOS (morphologic abnormality) |
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| has_related_synonym |
giant granulocellular Abrikosov's tumor Abrikosoff's granulous cell tumour malignant variant of Abrikosov's tumour Abrikosoff's tumor malignant variant of Abrikosov's tumor Abrikosoff's tumour Abrikosoff's granulous cell tumor Abrikosov's tumour giant granulocellular Abrikosov's tumour Abrikosov’s tumour Abrikosov’s tumor Abrikosov's tumor GCT |
|
| id |
EFO:1000284 |
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| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare |
|
| label |
Granular Cell Tumor |
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| notation |
EFO:1000284 |
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| preferred label |
Granular Cell Tumor |
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| prefLabel |
Granular Cell Tumor |
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| see also |
https://rarediseases.info.nih.gov/diseases/9618/granular-cell-tumor |
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| skos_exactMatch |
http://identifiers.org/mesh/C535558 http://purl.obolibrary.org/obo/NCIT_C3474 http://identifiers.org/mesh/D016586 http://purl.obolibrary.org/obo/DOID_2411 http://identifiers.org/medgen/88345 http://identifiers.org/snomedct/404035005 |
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| subClassOf |