loading...| Preferred Name | vasculitis | |
| Synonyms |
systemic vasculitis angiitis vasculitis |
|
| Definitions |
A group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. Behcet disease) to relatively minor skin disease. see infosheet: http://www.vasculitis.org.uk/content/downloads/understanding-vasculitis-factsheet-june-2014.pdf |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0006803 |
|
| comment |
see infosheet: http://www.vasculitis.org.uk/content/downloads/understanding-vasculitis-factsheet-june-2014.pdf |
|
| database_cross_reference |
SCTID:31996006 MeSH:D014657 MESH:D014657 Orphanet:52759 MEDGEN:12054 MedDRA:10047115 icd11.foundation:572581721 UMLS:C0042384 OMIM:615688 MedDRA:10036023 SNOMEDCT:31996006 Wikipedia:Vasculitis MONDO:0018882 NCIt:C26912 NCIT:C26912 DOID:865 GARD:18844 ICD10:M31 |
|
| definition |
A group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. Behcet disease) to relatively minor skin disease. |
|
| disease has inflammation site | ||
| gwas_trait |
true |
|
| has_exact_synonym |
vasculitis |
|
| has_narrow_synonym |
systemic vasculitis |
|
| has_related_synonym |
angiitis |
|
| id |
EFO:0006803 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_group_of_disorders http://purl.obolibrary.org/obo/mondo/mondo-base#disease_grouping |
|
| label |
vasculitis |
|
| located_in | ||
| notation |
EFO:0006803 |
|
| preferred label |
vasculitis |
|
| prefLabel |
vasculitis |
|
| skos_closeMatch | ||
| skos_exactMatch |
http://purl.obolibrary.org/obo/DOID_865 http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/572581721 http://identifiers.org/mesh/D014657 http://purl.obolibrary.org/obo/EFO_0006803 http://linkedlifedata.com/resource/umls/id/C0042384 http://identifiers.org/medgen/12054 http://purl.obolibrary.org/obo/NCIT_C26912 |
|
| term editor |
Sirarat Sarntivijai |
|
| subClassOf |
http://www.ebi.ac.uk/efo/EFO_0000408 |