loading...| Preferred Name | calcium metabolic disease | |
| Synonyms |
calcium metabolism disease calcium metabolism disorder calcium metabolic disease Calcium Metabolism Disorders calcium metabolic disorder disorder of calcium metabolism |
|
| Definitions |
Disorders in the processing of calcium in the body: its absorption, transport, storage, and utilization. Disorders of calcium metabolism occur when the body has too little or too much calcium. The serum level of calcium is closely regulated within a fairly limited range in the human body. In a healthy physiology, extracellular calcium levels are maintained within a tight range through the actions of parathyroid hormone, vitamin D and the calcium sensing receptor.[1] Disorders in calcium metabolism can lead to hypocalcemia, decreased plasma levels of calcium or hypercalcemia, elevated plasma calcium levels. Consider relocating this as a sibling of metabolic disease. Defined in terms of GO calcium ion homeostatis. Also consistent with HPO. Note advice from GO as calcium ions are neither created or destroyed is not metabolic process in terms of go, but name retained for purposes of consistency with e.g. Snomed and Mesh |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0005769 |
|
| comment |
Consider relocating this as a sibling of metabolic disease. Defined in terms of GO calcium ion homeostatis. Also consistent with HPO. Note advice from GO as calcium ions are neither created or destroyed is not metabolic process in terms of go, but name retained for purposes of consistency with e.g. Snomed and Mesh |
|
| database_cross_reference |
UMLS:C0006705 MESH:D002128 SNOMEDCT:190863003 MeSH:D002128 SNOMEDCT:71638002 SNOMEDCT:190874007 MONDO:0005557 ICD9CM:275.4 ICD9CM:275.40 ICD9:275.40 ICD9:275.49 SCTID:71638002 SNOMEDCT:267442002 DOID:10575 ICD9:275.4 MEDGEN:714 |
|
| definition |
Disorders in the processing of calcium in the body: its absorption, transport, storage, and utilization. Disorders of calcium metabolism occur when the body has too little or too much calcium. The serum level of calcium is closely regulated within a fairly limited range in the human body. In a healthy physiology, extracellular calcium levels are maintained within a tight range through the actions of parathyroid hormone, vitamin D and the calcium sensing receptor.[1] Disorders in calcium metabolism can lead to hypocalcemia, decreased plasma levels of calcium or hypercalcemia, elevated plasma calcium levels. |
|
| definition_citation |
http://en.wikipedia.org/wiki/Disorders_of_calcium_metabolism DOID:10575 |
|
| disease disrupts | ||
| gwas_trait |
true |
|
| has_exact_synonym |
calcium metabolic disease calcium metabolism disease Calcium Metabolism Disorders calcium metabolic disorder calcium metabolism disorder disorder of calcium metabolism |
|
| has_related_synonym |
calcium metabolism disease calcium metabolism disorder |
|
| id |
EFO:0005769 |
|
| in_subset | ||
| label |
calcium metabolic disease |
|
| notation |
EFO:0005769 |
|
| participates_in | ||
| preferred label |
calcium metabolic disease |
|
| prefLabel |
calcium metabolic disease |
|
| skos_exactMatch |
http://identifiers.org/mesh/D002128 http://identifiers.org/medgen/714 http://identifiers.org/snomedct/71638002 http://purl.obolibrary.org/obo/DOID_10575 |
|
| term editor |
Helen Parkinson |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://www.ebi.ac.uk/efo/EFO_0005769 | EFO | SAME_URI | |
| http://www.ebi.ac.uk/efo/EFO_0005769 | BMONT | SAME_URI | |
| http://www.ebi.ac.uk/efo/EFO_0005769 | EFO | SAME_URI | |
| http://purl.obolibrary.org/obo/MONDO_0005557 | GCBO | LOOM | |
| http://purl.obolibrary.org/obo/MONDO_0005557 | MONDO | LOOM | |
| http://purl.obolibrary.org/obo/MONDO_0005557 | DOVES | LOOM | |
| http://purl.obolibrary.org/obo/MONDO_0005557 | KTAO | LOOM | |
| http://purl.obolibrary.org/obo/MONDO_0005557 | OBA | LOOM | |
| http://www.ebi.ac.uk/efo/EFO_0005769 | EFO | LOOM | |
| http://www.ebi.ac.uk/efo/EFO_0005769 | BMONT | LOOM | |
| http://www.ebi.ac.uk/efo/EFO_0005769 | EFO | LOOM |