Cell Culture Ontology

Last uploaded: July 23, 2014

Preferred Name	small cell lung carcinoma
Synonyms	small cell cancer of the lung SCLC1 poorly differentiated endocrine neoplasm oat cell carcinoma (morphologic abnormality) oat cell carcinoma SCLC oat cell carcinoma of lung small cell cancer of the lung, somatic oat cell carcinoma of the lung small cell neuroendocrine carcinoma of the lung lung small cell neuroendocrine carcinoma oat cell lung carcinoma lung small cell carcinoma Small cell lung cancer lung oat cell carcinoma small cell carcinoma of the lung small cell lung cancer small-cell cancer of lung small cell carcinoma of lung small cell neuroendocrine carcinoma of lung small cell lung carcinoma
Definitions	Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized byrapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure.
ID	http://www.ebi.ac.uk/efo/EFO_0000702
closeMatch	http://identifiers.org/snomedct/76817009 http://identifiers.org/snomedct/74364000 http://linkedlifedata.com/resource/umls/id/C0149925 http://identifiers.org/snomedct/189555001
conformsTo	http://purl.obolibrary.org/obo/mondo/patterns/location.yaml http://purl.obolibrary.org/obo/mondo/patterns/small_cell_carcinoma.yaml
database_cross_reference	SCTID:254632001 UMLS:CN244903 ONCOTREE:SCLC MEDGEN:57450 UMLS:C0149925 icd11.foundation:1800431439 OMIM:182280 UMLS:C0262584 ICD10:C34.9 EFO:0000702 MONDO:0008433 MESH:D055752 MedDRA:10029882 Orphanet:70573 DOID:5409 DOID:5411 GARD:9344 ICD9:162.9 KEGG:05222 NCIT:C4917
definition	Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized byrapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure.
exactMatch	http://identifiers.org/mesh/D055752 http://purl.obolibrary.org/obo/NCIT_C4917 http://purl.obolibrary.org/obo/DOID_5409 http://linkedlifedata.com/resource/umls/id/CN244903 http://www.orpha.net/ORDO/Orphanet_70573 http://identifiers.org/omim/182280 http://identifiers.org/snomedct/254632001 http://linkedlifedata.com/resource/umls/id/C0262584 http://purl.obolibrary.org/obo/DOID_5411
gwas_trait	true
has_broad_synonym	poorly differentiated endocrine neoplasm oat cell carcinoma (morphologic abnormality) oat cell carcinoma SCLC
has_exact_synonym	oat cell carcinoma of lung small cell cancer of the lung, somatic oat cell carcinoma of the lung small cell neuroendocrine carcinoma of the lung lung small cell neuroendocrine carcinoma oat cell lung carcinoma lung small cell carcinoma Small cell lung cancer lung oat cell carcinoma small cell carcinoma of the lung small cell lung cancer small-cell cancer of lung small cell carcinoma of lung small cell neuroendocrine carcinoma of lung small cell lung carcinoma
has_related_synonym	small cell cancer of the lung SCLC1
IAO_0000233	https://github.com/monarch-initiative/mondo/issues/4521
id	EFO:0000702
in_subset	http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo#ordo_disease http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-base#nord_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_disorder
label	small cell lung carcinoma
narrowMatch	http://identifiers.org/snomedct/254633006
notation	EFO:0000702
preferred label	small cell lung carcinoma
prefLabel	small cell lung carcinoma
skos_exactMatch	http://identifiers.org/mesh/D055752 http://purl.obolibrary.org/obo/NCIT_C4917 https://omim.org/entry/182280 http://purl.obolibrary.org/obo/DOID_5409 http://purl.obolibrary.org/obo/EFO_0000702 http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/1800431439 http://identifiers.org/medgen/57450 http://purl.obolibrary.org/obo/Orphanet_70573 http://identifiers.org/snomedct/254632001 http://linkedlifedata.com/resource/umls/id/C0149925 http://purl.obolibrary.org/obo/DOID_5411
subClassOf	http://www.ebi.ac.uk/efo/EFO_0005220 http://www.ebi.ac.uk/efo/EFO_0008524 http://www.orpha.net/ORDO/Orphanet_271847 http://www.ebi.ac.uk/efo/EFO_0001071

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Mapping To	Ontology	Source
http://www.ebi.ac.uk/efo/EFO_0000702	EFO	SAME_URI
http://purl.obolibrary.org/obo/MONDO_0008433	MONDO	LOOM
http://id.nlm.nih.gov/mesh/D055752	MDM	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Small_Cell_Lung_Carcinoma	CSEO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D055752	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C04.588.894.797.520.109.220.624	RH-MESH	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4917	ROO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C08.381.540.140.750	RH-MESH	LOOM
http://www.ebi.ac.uk/efo/EFO_0000702	EFO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00038101	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/MONDO_0008433	DOVES	LOOM
http://purl.obolibrary.org/obo/OMIT_0026458	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C08.785.520.100.220.750	RH-MESH	LOOM
http://purl.bioontology.org/ontology/MESH/D055752	MESH	LOOM
rgo:30781	GAMUTS	LOOM
http://purl.obolibrary.org/obo/HP_0030357	HP	LOOM
http://purl.obolibrary.org/obo/HP_0030357	UPHENO	LOOM