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Cell Culture Ontology
| Preferred Name | medullary thyroid gland carcinoma | |
| Synonyms |
medullary thyroid cancer (MTC) thyroid cancer, medullary thyroid carcinoma, medullary THME thyroid gland medullary carcinoma thyroid medullary carcinoma medullary thyroid gland carcinoma medullary carcinoma of the thyroid gland medullary thyroid cancer medullary carcinoma of thyroid ultimobranchial thyroid tumour ultimobranchial thyroid tumor medullary thyroid carcinoma C cell carcinoma carcinoma, C-cell, malignant thyroid gland medullary cancer parafollicular cell carcinoma carcinoma of parafollicular cell medullary carcinoma of thyroid gland thyroid gland neuroendocrine carcinoma medullary carcinoma medullary carcinoma of the thyroid MTC |
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| Definitions |
A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis. Surgery is the preferred treatment for both primary lesions and recurrences. This carcinoma is generally not very sensitive to radiation and almost unresponsive to chemotherapy. |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0015277 |
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| database_cross_reference |
MEDGEN:66772 NANDO:2201054 UMLS:C0238462 Orphanet:1332 ONCOTREE:THME icd11.foundation:578519098 MedDRA:10027101 SCTID:255032005 DOID:3973 GARD:7004 HP:0002865 NCIT:C3879
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|
| definition |
A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis. Surgery is the preferred treatment for both primary lesions and recurrences. This carcinoma is generally not very sensitive to radiation and almost unresponsive to chemotherapy.
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| disease has location | ||
| has_exact_synonym |
thyroid gland medullary carcinoma thyroid medullary carcinoma medullary thyroid gland carcinoma medullary carcinoma of the thyroid gland medullary thyroid cancer medullary carcinoma of thyroid ultimobranchial thyroid tumour ultimobranchial thyroid tumor medullary thyroid carcinoma C cell carcinoma carcinoma, C-cell, malignant thyroid gland medullary cancer parafollicular cell carcinoma carcinoma of parafollicular cell medullary carcinoma of thyroid gland thyroid gland neuroendocrine carcinoma medullary carcinoma medullary carcinoma of the thyroid MTC
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| has_related_synonym |
medullary thyroid cancer (MTC) thyroid cancer, medullary thyroid carcinoma, medullary THME
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|
| id |
MONDO:0015277
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| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_disorder |
|
| label |
medullary thyroid gland carcinoma
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|
| notation |
MONDO:0015277
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|
| preferred label |
medullary thyroid gland carcinoma
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|
| prefLabel |
medullary thyroid gland carcinoma
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| skos_closeMatch | ||
| skos_exactMatch |
http://identifiers.org/medgen/66772 http://identifiers.org/snomedct/255032005 http://purl.obolibrary.org/obo/NCIT_C3879 http://purl.obolibrary.org/obo/Orphanet_1332 http://linkedlifedata.com/resource/umls/id/C0238462 http://purl.obolibrary.org/obo/DOID_3973 http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/578519098 |
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| subClassOf |
http://www.ebi.ac.uk/efo/EFO_0000313 |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
| Mapping To | Ontology | Source |
|---|---|---|
| http://purl.obolibrary.org/obo/MONDO_0015277 | OBA | SAME_URI |
| http://purl.obolibrary.org/obo/MONDO_0015277 | MONDO | SAME_URI |
| http://purl.obolibrary.org/obo/MONDO_0015277 | EFO | SAME_URI |
| http://purl.obolibrary.org/obo/MONDO_0015277 | DOVES | SAME_URI |
| http://purl.obolibrary.org/obo/MONDO_0015277 | OBA | LOOM |
| http://purl.obolibrary.org/obo/MONDO_0015277 | MONDO | LOOM |
| http://purl.obolibrary.org/obo/MONDO_0015277 | EFO | LOOM |
| http://purl.obolibrary.org/obo/MONDO_0015277 | DOVES | LOOM |