Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Abnormality of bone mineral density
Synonyms

Abnormality of bone mineralisation and ossification

Definitions

This term applies to all changes in bone mineral density which (depending on severity) can be seen on x-rays as a change in density and or structure of the bone. Changes may affect all bones of the organism, just certain bones or only parts of bones and include decreased mineralisation as may be seen in osteoporosis or increased mineralisation and or ossification as in osteopetrosis, exostoses or any kind of atopic calicfications of different origin and distribution. The overall amount of mineralization of the bone-organ can be measured as the amount of matter per cubic centimeter of bones, usually measured by densitometry of the lumbar spine or hip. The measurements are usually reported as g/cm3 or as a Z-score (the number of standard deviations above or below the mean for the patient's age and sex). Note that measurement with this method does not reflect local changes in other bones, and as such might not be correct with regard the hole bone-organ.

ID

http://purl.obolibrary.org/obo/HP_0004348

creation_date

2008-03-11T08:10:00Z

creator

https://orcid.org/0000-0002-0736-9199

database_cross_reference

UMLS:C4021657

definition

This term applies to all changes in bone mineral density which (depending on severity) can be seen on x-rays as a change in density and or structure of the bone. Changes may affect all bones of the organism, just certain bones or only parts of bones and include decreased mineralisation as may be seen in osteoporosis or increased mineralisation and or ossification as in osteopetrosis, exostoses or any kind of atopic calicfications of different origin and distribution. The overall amount of mineralization of the bone-organ can be measured as the amount of matter per cubic centimeter of bones, usually measured by densitometry of the lumbar spine or hip. The measurements are usually reported as g/cm3 or as a Z-score (the number of standard deviations above or below the mean for the patient's age and sex). Note that measurement with this method does not reflect local changes in other bones, and as such might not be correct with regard the hole bone-organ.

gwas_trait

true

has_exact_synonym

Abnormality of bone mineralisation and ossification

id

HP:0004348

label

Abnormality of bone mineral density

notation

HP:0004348

preferred label

Abnormality of bone mineral density

prefLabel

Abnormality of bone mineral density

subClassOf

http://purl.obolibrary.org/obo/HP_0003330

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