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Cell Culture Ontology
Last uploaded:
July 23, 2014
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| Id | http://purl.obolibrary.org/obo/CHEBI_28445
http://purl.obolibrary.org/obo/CHEBI_28445
|
|---|---|
| Preferred Name | vincristine |
| Definitions |
A vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer.
|
| Synonyms |
(+)-Vincristine
leucristine
leurocristine
22-oxo-vincaleukoblastine
22-Oxovincaleukoblastine
oncovin
vincristin
vinkristin
22-oxovincaleukoblastine
Vincristine
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. |
|---|---|
| preferred label |
vincristine
|
| label |
vincristine
|
| prefLabel |
vincristine
|
| database_cross_reference |
KEGG:C07204
PMID:18520608
SNOMEDCT:23079006
PMID:31048222
HMDB:HMDB0014681
PMID:30599272
CAS:57-22-7
Wikipedia:Vincristine
PMID:30604513
PMID:30277559
PMID:31296986
MeSH:D014750
SNOMEDCT:387126006
PMID:31214762
PMID:31161774
Drug_Central:2825
PMID:30429697
KNApSAcK:C00001783
DrugBank:DB00541
Beilstein:4779289
KEGG:D08679
PMID:30657998
MetaCyc:CPD-19894
NCIt:C933
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|
| notation |
CHEBI:28445
|
| in_subset | |
| inchi |
InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1
|
| has_related_synonym |
(+)-Vincristine
leucristine
leurocristine
22-oxo-vincaleukoblastine
22-Oxovincaleukoblastine
oncovin
vincristin
vinkristin
See more
See less
|
| id |
CHEBI:28445
|
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| formula |
C46H56N4O10
|
| subClassOf | |
| inchikey |
OGWKCGZFUXNPDA-XQKSVPLYSA-N
|
| mass |
824.95780
|
| monoisotopicmass |
824.39964
|
| has_alternative_id |
CHEBI:27289
CHEBI:9987
|
| type | |
| smiles |
[H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C=O)[C@@]1([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]1(C[C@@H]2C[N@](CCc3c1[nH]c1ccccc31)C[C@](O)(CC)C2)C(=O)OC
|
| has_role | |
| has_exact_synonym |
22-oxovincaleukoblastine
Vincristine
|
| has characteristic |
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