Cell Cycle Ontology

Last uploaded: June 26, 2014
Preferred Name

epistasis
Synonyms

epistatic

epistatic genetic interaction (sensu inequality)

Definitions

An effect in which individual perturbations of two different genes result in different mutant phenotypes, and the resulting phenotype of their combination (the double mutant) is equal to that of only one of the perturbations. With respect to any single quantifiable phenotype, this may be expressed as an inequality as: (a != wt AND b != wt AND a != b) AND (ab = a OR ab = b) where 'a' and 'b' are the observed phenotype values of the individual perturbations, 'ab' is the observed phenotype value of the double perturbation, 'wt' is the wild type phenotype value and 'a != b' indicates qualitatively or quantitatively different phenotypes.

ID

http://purl.obolibrary.org/obo/MI_0797

definition

An effect in which individual perturbations of two different genes result in different mutant phenotypes, and the resulting phenotype of their combination (the double mutant) is equal to that of only one of the perturbations. With respect to any single quantifiable phenotype, this may be expressed as an inequality as: (a != wt AND b != wt AND a != b) AND (ab = a OR ab = b) where 'a' and 'b' are the observed phenotype values of the individual perturbations, 'ab' is the observed phenotype value of the double perturbation, 'wt' is the wild type phenotype value and 'a != b' indicates qualitatively or quantitatively different phenotypes.

has_exact_synonym

epistatic

epistatic genetic interaction (sensu inequality)

has_obo_namespace

PSI-MI

id

MI:0797

in_subset

http://purl.obolibrary.org/obo/cco#PSI-MI_slim

label

epistasis

notation

MI:0797

prefLabel

epistasis

treeView

http://purl.obolibrary.org/obo/MI_0208

subClassOf

http://purl.obolibrary.org/obo/MI_0208

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