BRENDA Tissue and Enzyme Source Ontology

Last uploaded: February 4, 2022
Preferred Name

COS cell

Synonyms
Definitions

A cell line derived from the african green monkey and used for transfection and cloning. The cells are simian fibroblasts (cv 1 cells) transformed by sv40 that is deficient in the origin of replication region. They express large t antigen constitutively and if transfected with a vector containing a normal sv40 origin have all the other early viral genes necessary to generate multiple copies of the vector and thus to give very high levels of expression.

ID

http://purl.obolibrary.org/obo/BTO_0004055

definition

A cell line derived from the african green monkey and used for transfection and cloning. The cells are simian fibroblasts (cv 1 cells) transformed by sv40 that is deficient in the origin of replication region. They express large t antigen constitutively and if transfected with a vector containing a normal sv40 origin have all the other early viral genes necessary to generate multiple copies of the vector and thus to give very high levels of expression.

develops_from

http://purl.obolibrary.org/obo/BTO_0000318

has_obo_namespace

BrendaTissueOBO

id

BTO:0004055

label

COS cell

notation

BTO:0004055

prefLabel

COS cell

treeView

http://purl.obolibrary.org/obo/BTO_0000318

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