BRENDA Tissue and Enzyme Source Ontology

Last uploaded: February 4, 2022
Preferred Name

A3 cell

Synonyms

Jurkat A3 cell

Jurkat clone A3 cell

Definitions

Human T lymphocyte, acute T cell leukemia cell line. Morphology: lymphoblastoid. The A3 subclone was derived from a Jurkat cell line obtained from the laboratory of Gerald Crabtree at Stanford University. The Jurkat cells were treated with Fas Antibody and isolated by limiting dilution to obtain a cell line that had a low spontaneous rate of resistance to Fas-medicated apoptosis. The resulting wild-type A3 subclone is very sensitive to Fas-mediated apoptosis.

ID

http://purl.obolibrary.org/obo/BTO_0001342

definition

Human T lymphocyte, acute T cell leukemia cell line. Morphology: lymphoblastoid. The A3 subclone was derived from a Jurkat cell line obtained from the laboratory of Gerald Crabtree at Stanford University. The Jurkat cells were treated with Fas Antibody and isolated by limiting dilution to obtain a cell line that had a low spontaneous rate of resistance to Fas-medicated apoptosis. The resulting wild-type A3 subclone is very sensitive to Fas-mediated apoptosis.

develops_from

http://purl.obolibrary.org/obo/BTO_0000661

has_obo_namespace

BrendaTissueOBO

has_related_synonym

Jurkat A3 cell

Jurkat clone A3 cell

id

BTO:0001342

label

A3 cell

notation

BTO:0001342

prefLabel

A3 cell

treeView

http://purl.obolibrary.org/obo/BTO_0000661

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http://purl.obolibrary.org/obo/CLO_0001577 CLO LOOM