loading...| Preferred Name | tumor necrosis factor-alpha | |
| Synonyms |
TNF-alpha; tumor necrosis factor |
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| Definitions |
Tumor necrosis factor (TNF, cachexin or cachectin formerly known as tumor necrosis factor-alpha or TNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. |
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| ID |
http://www.ebi.ac.uk/efo/EFO_0003271 |
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| database cross reference |
MeSH:D014409 DSSTox_CID:40634 CASRN:308079-78-9 OMIM:191160 |
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| definition |
Tumor necrosis factor (TNF, cachexin or cachectin formerly known as tumor necrosis factor-alpha or TNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. |
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| definition_citation | ||
| hasExactSynonym |
TNF-alpha; tumor necrosis factor |
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| imported from | ||
| label |
tumor necrosis factor-alpha |
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| note |
Tumor necrosis factor (TNF, cachexin or cachectin formerly known as tumor necrosis factor-alpha or TNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. |
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| preferred label |
tumor necrosis factor-alpha |
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| prefixIRI |
efo:EFO_0003271 |
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| prefLabel |
tumor necrosis factor-alpha |
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| term editor |
Tomasz Adamusiak Ele Holloway James Malone |
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| textual definition |
Tumor necrosis factor (TNF, cachexin or cachectin formerly known as tumor necrosis factor-alpha or TNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. |
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| subClassOf |