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The Biomarker Ontology
| Preferred Name | Histologic Grade | |
| Synonyms |
histological_grade Grade (high/low) Tumor_Grade Overall Tumor Grade histological grade Histologic Grade Tumor Grade Histopathologic Grade HISTOLOGY_GRADE Histopathology Grade Grade Grading OVLTGRD grade grading |
|
| Definitions |
The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C18000 |
|
| ALT_DEFINITION |
A description of a tumor based on how abnormal the cancer cells look under a microscope and how quickly the tumor is likely to grow and spread. Grading systems are different for each type of cancer. An assigned tumor grade based on a defined scoring system.
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|
| code |
C18000
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|
| Contributing_Source |
CDISC CPTAC ICDC NAACCR PCDC
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|
| definition |
The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems.
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|
| Has_PCDC_Data_Type | ||
| Has_PCDC_GCT_Permissible_Value |
http://purl.obolibrary.org/obo/NCIT_C43234 http://purl.obolibrary.org/obo/NCIT_C28079 http://purl.obolibrary.org/obo/NCIT_C28077 |
|
| Has_PCDC_OS_Authorized_Value |
http://purl.obolibrary.org/obo/NCIT_C43234 http://purl.obolibrary.org/obo/NCIT_C28079 http://purl.obolibrary.org/obo/NCIT_C28077 |
|
| hasExactSynonym |
histological_grade Grade (high/low) Tumor_Grade Overall Tumor Grade histological grade Histologic Grade Tumor Grade Histopathologic Grade HISTOLOGY_GRADE Histopathology Grade Grade Grading OVLTGRD grade grading
|
|
| imported from | ||
| in subset |
http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C179490 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C61410 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C165451 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C177396 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C66830 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C186764 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C166372 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C166373 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C156953 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C156952 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C159417 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C159416 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C159419 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C160911 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C132262 http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C132263 |
|
| isPrognosticBiomarkerFor | ||
| label |
Histologic Grade
|
|
| Legacy Concept Name |
Histopathologic_Grade
|
|
| note |
The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems.
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|
| preferred label |
Histologic Grade
|
|
| Preferred_Name |
Histologic Grade
|
|
| prefixIRI |
NCIT:C18000
|
|
| prefLabel |
Histologic Grade
|
|
| Semantic_Type |
Qualitative Concept
|
|
| textual definition |
The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems.
|
|
| UMLS_CUI |
C0919553
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|
| subClassOf |
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| No notes to display |