BioModels Ontology

Last uploaded: April 3, 2012
Preferred Name

clobetasol
Synonyms
Definitions

16beta-Methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.

ID

http://purl.obolibrary.org/obo/CHEBI_205919

alternative term

(11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione

clobetasol

[H][C@@]12C[C@H](C)[C@](O)(C(=O)CCl)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C

21-chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione

clobetasolum

InChIKey=FCSHDIVRCWTZOX-DVTGEIKXSA-N

C22H28ClFO4

InChI=1S/C22H28ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

definition

16beta-Methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.

has role

http://purl.obolibrary.org/obo/CHEBI_35472

label

clobetasol

prefixIRI

CHEBI:205919

prefLabel

clobetasol

subClassOf

http://purl.obolibrary.org/obo/CHEBI_36885

http://purl.obolibrary.org/obo/CHEBI_24261

http://purl.obolibrary.org/obo/CHEBI_35342

http://purl.obolibrary.org/obo/CHEBI_47909

http://purl.obolibrary.org/obo/CHEBI_35346

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http://purl.obolibrary.org/obo/CHEBI_205919 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_205919 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_205919 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_205919 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_205919 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_205919 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_205919 DRON SAME_URI
http://www.co-ode.org/ontologies/galen#Clobetasol GALEN LOOM
http://purl.obolibrary.org/obo/OMIT_0004303 OMIT LOOM
http://www.drugbank.ca/drugs/DB01013 FTC LOOM
http://purl.bioontology.org/ontology/MESH/D002990 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.908.093.250 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3049 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008992 OCHV LOOM
http://purl.bioontology.org/ontology/ATC/D07AD01 ATC LOOM
http://stirdf.jst.go.jp/id/200907001320268440 IOBC LOOM
http://purl.bioontology.org/ontology/RCD/x01MZ RCD LOOM
http://purl.bioontology.org/ontology/SNMI/C-91360 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147776 NDFRT LOOM
http://purl.obolibrary.org/obo/CHEBI_205919 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_205919 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_205919 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_205919 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_205919 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_205919 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_205919 DRON LOOM
http://purl.jp/bio/4/id/200906049539861170 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/419129004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4019684 VANDF LOOM
http://purl.obolibrary.org/obo/NCIT_C65339 BERO LOOM
http://purl.obolibrary.org/obo/MESH_D002990 BERO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65339 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002990 RH-MESH LOOM
https://go.drugbank.com/drugs/DB11750 MDM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018743 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RXNORM/2590 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/004480 NDDF LOOM