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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C99766
http://purl.obolibrary.org/obo/NCIT_C99766
|
|---|---|
| Preferred Name | Adagloxad Simolenin |
| Definitions |
A carbohydrate-based immunostimulant comprised of the Globo H hexasaccharide 1 (Globo H) epitope linked to the immunostimulant carrier protein keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Upon administration of adagloxad simolenin, the carbohydrate antigen Globo H may stimulate a cytotoxic T-lymphocyte (CTL) response against Globo H-expressing tumor cells, thereby decreasing tumor cell proliferation. Globo H is a tumor associated antigen (TAA) commonly found on a variety of tumor cells including breast cancer cells. KLH improves antigenic immune recognition and T-cell responses.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A carbohydrate-based immunostimulant comprised of the Globo H hexasaccharide 1 (Globo H) epitope linked to the immunostimulant carrier protein keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Upon administration of adagloxad simolenin, the carbohydrate antigen Globo H may stimulate a cytotoxic T-lymphocyte (CTL) response against Globo H-expressing tumor cells, thereby decreasing tumor cell proliferation. Globo H is a tumor associated antigen (TAA) commonly found on a variety of tumor cells including breast cancer cells. KLH improves antigenic immune recognition and T-cell responses. |
|---|---|
| prefLabel | Adagloxad Simolenin
|
| label | Adagloxad Simolenin
|
| NCI_META_CUI | CL433491
|
| PDQ_Closed_Trial_Search_ID | 724401
|
| code | C99766
|
| Has_Target | |
| prefixIRI | NCIT:C99766
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| in_subset |
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| Display_Name | Adagloxad Simolenin
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| Preferred_Name | Adagloxad Simolenin
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| FDA_UNII_Code | UCG949AA7Z
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Adagloxad Simolenin
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| CAS_Registry | 1458687-85-8
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| NCI_Drug_Dictionary_ID | 724401
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 724401
|
| Semantic_Type | Pharmacologic Substance
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