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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C99564
http://purl.obolibrary.org/obo/NCIT_C99564
|
|---|---|
| Preferred Name | Actinomycin C3 |
| Definitions |
A natural analogue of actinomycin, a chromopeptide antineoplastic antibiotic isolated from the bacterial genus Streptomyces. Actinomycin C3 inhibits DNA replication as well as RNA and protein synthesis by various mechanisms such as intercalating into the minor groove of DNA and interfering with the function of topoisomerase II.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A natural analogue of actinomycin, a chromopeptide antineoplastic antibiotic isolated from the bacterial genus Streptomyces. Actinomycin C3 inhibits DNA replication as well as RNA and protein synthesis by various mechanisms such as intercalating into the minor groove of DNA and interfering with the function of topoisomerase II. |
|---|---|
| prefLabel | Actinomycin C3
|
| label | Actinomycin C3
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| code | C99564
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| prefixIRI | NCIT:C99564
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| in_subset | |
| Preferred_Name | Actinomycin C3
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| FDA_UNII_Code | 6Z5DS38J6F
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| Contributing_Source | FDA
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| Chemical_Formula | C64H90N12O16
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| Maps_To | Actinomycin C3
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| CAS_Registry | 6156-47-4
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| NSC Number | 87221
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| PubMedID_Primary_Reference | 10888331
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
Antibiotic
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| UMLS_CUI | C0604201
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