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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C99122
http://purl.obolibrary.org/obo/NCIT_C99122
|
|---|---|
| Preferred Name | North American Ginseng Extract AFX-2 |
| Definitions |
An orally available proprietary aqueous extract from the North American ginseng (Panax quinquefolius) dried root, primarily containing poly-furanosyl-pyranosyl-saccharides, with potential immunostimulating activity. Upon administration, North American ginseng extract AFX-2 may stimulate the proliferation and activation of B-lymphocytes and stimulates IgG production by B cells. Also, this agent induces maturation of dendritic cells, induces T cell proliferation and activates peritoneal exudate macrophages leading to an increase in the production of the cytokines interleukin -1 and -6, tumor necrosis factor-alpha, interferon-gamma and nitric oxide.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally available proprietary aqueous extract from the North American ginseng (Panax quinquefolius) dried root, primarily containing poly-furanosyl-pyranosyl-saccharides, with potential immunostimulating activity. Upon administration, North American ginseng extract AFX-2 may stimulate the proliferation and activation of B-lymphocytes and stimulates IgG production by B cells. Also, this agent induces maturation of dendritic cells, induces T cell proliferation and activates peritoneal exudate macrophages leading to an increase in the production of the cytokines interleukin -1 and -6, tumor necrosis factor-alpha, interferon-gamma and nitric oxide. |
|---|---|
| prefLabel | North American Ginseng Extract AFX-2
|
| label | North American Ginseng Extract AFX-2
|
| PDQ_Closed_Trial_Search_ID | 715600
|
| code | C99122
|
| prefixIRI | NCIT:C99122
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| in_subset | |
| Preferred_Name | North American Ginseng Extract AFX-2
|
| Maps_To | North American Ginseng Extract AFX-2
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| NCI_Drug_Dictionary_ID | 715600
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 715600
|
| Semantic_Type |
Pharmacologic Substance
Plant
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| UMLS_CUI | C1722695
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