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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C98296
http://purl.obolibrary.org/obo/NCIT_C98296
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|---|---|
| Preferred Name | Monoclonal Antibody CEP-37250/KHK2804 |
| Definitions |
A humanized monoclonal antibody targeting glycolipids, with potential immunomodulating and antineoplastic activity. Upon administration, monoclonal antibody CEP-37250/KHK2804 targets and binds to a specific tumor antigen, thereby stimulating the immune system to exert an antibody-dependent cellular cytotoxicity (ADCC) against the tumor associated antigen (TAA)-expressing cancer cells. This agent has shown to be active in both wild-type and mutant K-RAS-expressing colorectal cancer cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A humanized monoclonal antibody targeting glycolipids, with potential immunomodulating and antineoplastic activity. Upon administration, monoclonal antibody CEP-37250/KHK2804 targets and binds to a specific tumor antigen, thereby stimulating the immune system to exert an antibody-dependent cellular cytotoxicity (ADCC) against the tumor associated antigen (TAA)-expressing cancer cells. This agent has shown to be active in both wild-type and mutant K-RAS-expressing colorectal cancer cells. |
|---|---|
| prefLabel | Monoclonal Antibody CEP-37250/KHK2804
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| label | Monoclonal Antibody CEP-37250/KHK2804
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| NCI_META_CUI | CL432414
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| PDQ_Closed_Trial_Search_ID | 714212
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| code | C98296
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| prefixIRI | NCIT:C98296
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| in_subset |
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| Display_Name | Monoclonal Antibody CEP-37250/KHK2804
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| Preferred_Name | Monoclonal Antibody CEP-37250/KHK2804
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| Contributing_Source | CTRP
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| Maps_To | Monoclonal Antibody CEP-37250/KHK2804
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| NCI_Drug_Dictionary_ID | 714212
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 714212
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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