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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C98234
http://purl.obolibrary.org/obo/NCIT_C98234
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|---|---|
| Preferred Name | Biguanide Antidiabetic Agent |
| Definitions |
Any antidiabetic agent with the biguanide base structure or phenformin derivatives with antihyperglycemic activity. Biguanide antidiabetic agents activate AMP-activated protein kinase (AMPK) resulting in decreased glucose production in the liver, increased peripheral glucose uptake and improved utilization of glucose. Biguanide-based antidiabetic agents do not cause hypoglycemia. In addition, biguanide antidiabetics decrease absorption of glucose from the gastrointestinal tract.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any antidiabetic agent with the biguanide base structure or phenformin derivatives with antihyperglycemic activity. Biguanide antidiabetic agents activate AMP-activated protein kinase (AMPK) resulting in decreased glucose production in the liver, increased peripheral glucose uptake and improved utilization of glucose. Biguanide-based antidiabetic agents do not cause hypoglycemia. In addition, biguanide antidiabetics decrease absorption of glucose from the gastrointestinal tract. |
|---|---|
| prefLabel | Biguanide Antidiabetic Agent
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| label | Biguanide Antidiabetic Agent
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| code | C98234
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| prefixIRI | NCIT:C98234
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| in_subset | |
| Preferred_Name | Biguanide Antidiabetic Agent
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| Contributing_Source | GDC
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| Maps_To | Biguanide
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Pharmacologic Substance
Chemical Viewed Functionally
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| UMLS_CUI | C3273895
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