Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C981
http://purl.obolibrary.org/obo/NCIT_C981
|
|---|---|
| Preferred Name | Decitabine |
| Definitions |
A cytidine antimetabolite analogue with potential antineoplastic activity. Decitabine incorporates into DNA and inhibits DNA methyltransferase, resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. (NCI04)
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cytidine antimetabolite analogue with potential antineoplastic activity. Decitabine incorporates into DNA and inhibits DNA methyltransferase, resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. (NCI04) |
|---|---|
| prefLabel | Decitabine
|
| label | Decitabine
|
| CHEBI_ID | CHEBI:50131
|
| PDQ_Closed_Trial_Search_ID | 39299
|
| code | C981
|
| Has_Target | |
| prefixIRI | NCIT:C981
|
| in_subset |
See more
See less
|
| Display_Name | Decitabine
|
| Preferred_Name | Decitabine
|
| FDA_UNII_Code | 776B62CQ27
|
| Contributing_Source |
CTRP
FDA
|
| Chemical_Formula | C8H12N4O4
|
| Maps_To | Decitabine
|
| CAS_Registry | 2353-33-5
|
| NSC Number | 127716
|
| NCI_Drug_Dictionary_ID | 39299
|
| Legacy Concept Name | Decitabine
|
| type | |
| ALT_DEFINITION | A drug that is used to treat myelodysplastic syndromes and is being studied in the treatment of other types of cancer. It is a type of antimetabolite.
|
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39299
|
| Accepted_Therapeutic_Use_For | Myelodysplastic Syndrome
|
| Semantic_Type |
Pharmacologic Substance
Nucleic Acid, Nucleoside, or Nucleotide
|
| UMLS_CUI | C0049065
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |