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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C980
http://purl.obolibrary.org/obo/NCIT_C980
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|---|---|
| Preferred Name | Dihydro-5-Azacytidine |
| Definitions |
A synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase, thereby interfering with abnormal DNA methylation patterns that are associated with genetic instability in some tumor cells. Inhibition of this enzyme may restore expression of tumor-suppressor genes and result in antitumor activity. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase, thereby interfering with abnormal DNA methylation patterns that are associated with genetic instability in some tumor cells. Inhibition of this enzyme may restore expression of tumor-suppressor genes and result in antitumor activity. (NCI04) |
|---|---|
| label | Dihydro-5-Azacytidine
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| prefLabel | Dihydro-5-Azacytidine
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| Legacy Concept Name | Dihydro-5-Azacytidine
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| in_subset |
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| Preferred_Name | Dihydro-5-Azacytidine
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| Is_Value_For_GDC_Property | |
| Chemical_Formula | C8H14N4O5
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| Display_Name | Dihydro-5-Azacytidine
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| Maps_To | Dihydro-5-Azacytidine
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| PDQ_Open_Trial_Search_ID | 39220
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| Has_Target | |
| UMLS_CUI | C0048906
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| FDA_UNII_Code | 0627D8VG1C
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| prefixIRI | NCIT:C980
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| NCI_Drug_Dictionary_ID | 39220
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| Contributing_Source |
CTRP
FDA
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| subClassOf | |
| code | C980
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| type | |
| NSC Number | 264880
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| PDQ_Closed_Trial_Search_ID | 39220
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| Semantic_Type |
Pharmacologic Substance
Nucleic Acid, Nucleoside, or Nucleotide
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| CAS_Registry | 62488-57-7
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| Delete | Subject | Author | Type | Created |
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