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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C97710
http://purl.obolibrary.org/obo/NCIT_C97710
|
|---|---|
| Preferred Name | Ansamitomicin P-3 |
| Definitions |
An ansamacrolide and maytansine analogue originally isolated from the Ethiopian shrub Maytenus serrata with antineoplastic activity. Ansamitomicin P-3 binds to tubulin at the maytansine-binding site, thereby inhibiting microtubule assembly, inducing microtubule disassembly, and disrupting mitosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An ansamacrolide and maytansine analogue originally isolated from the Ethiopian shrub Maytenus serrata with antineoplastic activity. Ansamitomicin P-3 binds to tubulin at the maytansine-binding site, thereby inhibiting microtubule assembly, inducing microtubule disassembly, and disrupting mitosis. |
|---|---|
| prefLabel | Ansamitomicin P-3
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| label | Ansamitomicin P-3
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| code | C97710
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| prefixIRI | NCIT:C97710
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| in_subset | |
| Preferred_Name | Ansamitomicin P-3
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| FDA_UNII_Code | 7SUK7876BG
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| Contributing_Source | FDA
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| Chemical_Formula | C32H43ClN2O9
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| Maps_To | Ansamitomicin P-3
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| CAS_Registry | 66547-09-9
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0952781
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