loading...| Preferred Name | Non-nucleoside Reverse Transcriptase Inhibitor | |
| Synonyms |
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| Definitions |
A substance structurally unlike a nucleoside molecule that is capable of inhibiting the function of a reverse transcriptase. These compounds do not bind to the active site of the polymerase but in a less conserved pocket near the active site, causing a distortion in the shape of the active site and resulting in inhibition of enzymatic function, chain termination, and inhibition of viral replication. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C97453 |
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| code |
C97453 |
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| definition |
A substance structurally unlike a nucleoside molecule that is capable of inhibiting the function of a reverse transcriptase. These compounds do not bind to the active site of the polymerase but in a less conserved pocket near the active site, causing a distortion in the shape of the active site and resulting in inhibition of enzymatic function, chain termination, and inhibition of viral replication. |
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| label |
Non-nucleoside Reverse Transcriptase Inhibitor |
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| Preferred_Name |
Non-nucleoside Reverse Transcriptase Inhibitor |
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| prefixIRI |
NCIT:C97453 |
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| prefLabel |
Non-nucleoside Reverse Transcriptase Inhibitor |
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| Semantic_Type |
Chemical Viewed Functionally |
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| UMLS_CUI |
C1373120 |
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| subClassOf |