Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C974 http://purl.obolibrary.org/obo/NCIT_C974
Preferred Name	Formestane
Definitions	A synthetic steroidal substance with antineoplastic activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. (NCI04)
Type	http://www.w3.org/2002/07/owl#Class

definition	A synthetic steroidal substance with antineoplastic activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. (NCI04)
prefLabel	Formestane
label	Formestane
PDQ_Closed_Trial_Search_ID	41766
code	C974
prefixIRI	NCIT:C974
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Formestane
FDA_UNII_Code	PUB9T8T355
Contributing_Source	FDA
Chemical_Formula	C19H26O3
Maps_To	Formestane
CAS_Registry	566-48-3
NCI_Drug_Dictionary_ID	41766
Legacy Concept Name	Formestane
type	http://www.w3.org/2002/07/owl#Class
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C2017
PDQ_Open_Trial_Search_ID	41766
Semantic_Type	Organic Chemical Pharmacologic Substance
UMLS_CUI	C0048306

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