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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C96934
http://purl.obolibrary.org/obo/NCIT_C96934
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|---|---|
| Preferred Name | Paclitaxel Ceribate |
| Definitions |
The ceribate ester form of paclitaxel, a compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to and stabilizes tubulin thereby inhibiting the disassembly of microtubules, resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein B-cell Leukemia 2 (BCL2).
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The ceribate ester form of paclitaxel, a compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to and stabilizes tubulin thereby inhibiting the disassembly of microtubules, resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein B-cell Leukemia 2 (BCL2). |
|---|---|
| prefLabel | Paclitaxel Ceribate
|
| label | Paclitaxel Ceribate
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| code | C96934
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| Has_Target | |
| prefixIRI | NCIT:C96934
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| in_subset | |
| Preferred_Name | Paclitaxel Ceribate
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| FDA_UNII_Code | B3C86E80A0
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| Contributing_Source | FDA
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| Chemical_Formula | C51H57NO18
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| Maps_To | Paclitaxel Ceribate
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| CAS_Registry | 186040-50-6
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C3273125
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