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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C95888
http://purl.obolibrary.org/obo/NCIT_C95888
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|---|---|
| Preferred Name | Plocabulin |
| Definitions |
A marine-derived, synthetically produced compound with potential antineoplastic activity. Plocabulin covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A marine-derived, synthetically produced compound with potential antineoplastic activity. Plocabulin covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death. |
|---|---|
| label | Plocabulin
|
| prefLabel | Plocabulin
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| in_subset |
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| Preferred_Name | Plocabulin
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| Is_Value_For_GDC_Property | |
| Display_Name | Plocabulin
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| Maps_To | Plocabulin
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| PDQ_Open_Trial_Search_ID | 696184
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| UMLS_CUI | C3272412
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| FDA_UNII_Code | 52Y8L60CR7
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| prefixIRI | NCIT:C95888
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| NCI_Drug_Dictionary_ID | 696184
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| Contributing_Source |
CTRP
FDA
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| subClassOf | |
| code | C95888
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| type | |
| PDQ_Closed_Trial_Search_ID | 696184
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| Semantic_Type | Pharmacologic Substance
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| CAS_Registry | 960210-99-5
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