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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C95861
http://purl.obolibrary.org/obo/NCIT_C95861
|
|---|---|
| Preferred Name | Puromycin-Sensitive Aminopeptidase |
| Definitions |
Puromycin-sensitive aminopeptidase (919 aa, ~103 kDa) is encoded by the human NPEPPS gene. This protein plays a role in peptide cleavage.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Puromycin-sensitive aminopeptidase (919 aa, ~103 kDa) is encoded by the human NPEPPS gene. This protein plays a role in peptide cleavage. |
|---|---|
| prefLabel | Puromycin-Sensitive Aminopeptidase
|
| label | Puromycin-Sensitive Aminopeptidase
|
| code | C95861
|
| prefixIRI | NCIT:C95861
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| OMIM_Number | 606793
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| in_subset | |
| Display_Name | Puromycin-Sensitive Aminopeptidase
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| Preferred_Name | Puromycin-Sensitive Aminopeptidase
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| Contributing_Source | CTRP
|
| Swiss_Prot | P55786
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| DesignNote | Puromycin-sensitive aminopeptidase may have hyperphosphorylated tau as a substrate. Enhancement of the activity of the enzyme is a candidate therapy for neuropathies where tau accumulation occurs, such as Alzheimer disease. (Hum. Mol. Genet. 2011; 20: doi: 10.1093/hmg/ddr065.)
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
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| UMLS_CUI | C1721284
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