Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C95734
http://purl.obolibrary.org/obo/NCIT_C95734
|
|---|---|
| Preferred Name | Anti-VEGFR3 Monoclonal Antibody IMC-3C5 |
| Definitions |
A fully-human monoclonal antibody directed against human vascular endothelial growth factor receptor 3 (VEGFR-3; Flt-4) with antiangiogenic activity. Anti-VEGFR-3 monoclonal antibody IMC-3C5 specifically binds to and inhibits VEGFR-3, which may result in inhibition of tumor angiogenesis and a decrease in tumor nutrient supply. VEGFR-3 plays a critical role in the embryonic vascular system development but is restricted postnatally to endothelial cells of lymphatic vessels and found to be expressed in many solid and hematologic malignancies.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A fully-human monoclonal antibody directed against human vascular endothelial growth factor receptor 3 (VEGFR-3; Flt-4) with antiangiogenic activity. Anti-VEGFR-3 monoclonal antibody IMC-3C5 specifically binds to and inhibits VEGFR-3, which may result in inhibition of tumor angiogenesis and a decrease in tumor nutrient supply. VEGFR-3 plays a critical role in the embryonic vascular system development but is restricted postnatally to endothelial cells of lymphatic vessels and found to be expressed in many solid and hematologic malignancies. |
|---|---|
| prefLabel | Anti-VEGFR3 Monoclonal Antibody IMC-3C5
|
| label | Anti-VEGFR3 Monoclonal Antibody IMC-3C5
|
| NCI_META_CUI | CL428195
|
| PDQ_Closed_Trial_Search_ID | 695064
|
| code | C95734
|
| Has_Target | |
| prefixIRI | NCIT:C95734
|
| in_subset |
See more
See less
|
| Display_Name | Anti-VEGFR3 Monoclonal Antibody IMC-3C5
|
| Preferred_Name | Anti-VEGFR3 Monoclonal Antibody IMC-3C5
|
| Contributing_Source | CTRP
|
| Maps_To | Anti-VEGFR3 Monoclonal Antibody IMC-3C5
|
| NCI_Drug_Dictionary_ID | 695064
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 695064
|
| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |