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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C95704
http://purl.obolibrary.org/obo/NCIT_C95704
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|---|---|
| Preferred Name | Anti-ANG2 Monoclonal Antibody MEDI-3617 |
| Definitions |
A fully human IgG1 monoclonal antibody against angiopoietin 2 (ANG2), with potential antiangiogenic activity. Anti-ANG2 monoclonal antibody MEDI-3617 binds to Ang2 and interferes with the interaction between Ang2 and its receptor TEK tyrosine kinase (Tie2), thereby resulting in the disruption of vascular remodeling. This may inhibit angiogenesis and may eventually lead to an inhibition of tumor cell proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A fully human IgG1 monoclonal antibody against angiopoietin 2 (ANG2), with potential antiangiogenic activity. Anti-ANG2 monoclonal antibody MEDI-3617 binds to Ang2 and interferes with the interaction between Ang2 and its receptor TEK tyrosine kinase (Tie2), thereby resulting in the disruption of vascular remodeling. This may inhibit angiogenesis and may eventually lead to an inhibition of tumor cell proliferation. |
|---|---|
| prefLabel | Anti-ANG2 Monoclonal Antibody MEDI-3617
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| label | Anti-ANG2 Monoclonal Antibody MEDI-3617
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| NCI_META_CUI | CL428170
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| PDQ_Closed_Trial_Search_ID | 690474
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| code | C95704
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| Has_Target | |
| prefixIRI | NCIT:C95704
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| in_subset |
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| Display_Name | Anti-ANG2 Monoclonal Antibody MEDI-3617
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| Preferred_Name | Anti-ANG2 Monoclonal Antibody MEDI-3617
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| FDA_UNII_Code | 6RH6DL8R4L
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Anti-ANG2 Monoclonal Antibody MEDI-3617
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| CAS_Registry | 1415642-51-1
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| NCI_Drug_Dictionary_ID | 690474
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 690474
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| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
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