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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C954
http://purl.obolibrary.org/obo/NCIT_C954
|
|---|---|
| Preferred Name | Tauromustine |
| Definitions |
A water-soluble taurine-based nitrosourea with potential antineoplastic activity. Tauromustine alkylates DNA and causes DNA cross links independent of cell cycle, thereby resulting in disruption of DNA function and induction of apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A water-soluble taurine-based nitrosourea with potential antineoplastic activity. Tauromustine alkylates DNA and causes DNA cross links independent of cell cycle, thereby resulting in disruption of DNA function and induction of apoptosis. |
|---|---|
| prefLabel | Tauromustine
|
| label | Tauromustine
|
| PDQ_Closed_Trial_Search_ID | 40279
|
| code | C954
|
| prefixIRI | NCIT:C954
|
| in_subset | |
| Preferred_Name | Tauromustine
|
| FDA_UNII_Code | 511F69K76Y
|
| Contributing_Source | FDA
|
| Chemical_Formula | C7H15ClN4O4S
|
| Maps_To | Tauromustine
|
| CAS_Registry | 85977-49-7
|
| NCI_Drug_Dictionary_ID | 40279
|
| Legacy Concept Name | Tauromustine
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 40279
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C0044133
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