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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C950
http://purl.obolibrary.org/obo/NCIT_C950
|
|---|---|
| Preferred Name | Anaxirone |
| Definitions |
A synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA synthesis. This agent has been shown to exhibit a broad spectrum of antineoplastic activity against experimental tumors, including those resistant to other alkylating agents.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA synthesis. This agent has been shown to exhibit a broad spectrum of antineoplastic activity against experimental tumors, including those resistant to other alkylating agents. |
|---|---|
| prefLabel | Anaxirone
|
| label | Anaxirone
|
| PDQ_Closed_Trial_Search_ID | 39194
|
| code | C950
|
| prefixIRI | NCIT:C950
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| in_subset | |
| Preferred_Name | Anaxirone
|
| FDA_UNII_Code | 36R61Y789T
|
| Contributing_Source | FDA
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| Chemical_Formula | C11H15N3O5
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| Maps_To | Anaxirone
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| CAS_Registry | 77658-97-0
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| NSC Number | 332488
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| NCI_Drug_Dictionary_ID | 39194
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| Legacy Concept Name | Anaxirone
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39194
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0043767
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