loading...| Preferred Name | Zidovudine | |
| Synonyms |
|
|
| Definitions |
A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C947 |
|
| Accepted_Therapeutic_Use_For |
AIDs-related complex; HIV infection; HIV transmission, prevention |
|
| ALT_DEFINITION |
A drug that inhibits the human immunodeficiency virus (HIV) that causes AIDS. It is a type of systemic antiviral. |
|
| CAS_Registry |
30516-87-1 |
|
| CHEBI_ID |
CHEBI:10110 |
|
| Chemical_Formula |
C10H13N5O4 |
|
| code |
C947 |
|
| Contributing_Source |
CTRP FDA |
|
| definition |
A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines. (NCI04) |
|
| Display_Name |
Zidovudine |
|
| FDA_UNII_Code |
4B9XT59T7S |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Zidovudine |
|
| Legacy Concept Name |
Zidovudine |
|
| NCI_Drug_Dictionary_ID |
40121 |
|
| NSC Number |
602670 |
|
| PDQ_Closed_Trial_Search_ID |
40121 |
|
| PDQ_Open_Trial_Search_ID |
40121 |
|
| Preferred_Name |
Zidovudine |
|
| prefixIRI |
NCIT:C947 |
|
| prefLabel |
Zidovudine |
|
| Semantic_Type |
Pharmacologic Substance Nucleic Acid, Nucleoside, or Nucleotide |
|
| UMLS_CUI |
C0043474 |
|
| subClassOf |