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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C94206
http://purl.obolibrary.org/obo/NCIT_C94206
|
|---|---|
| Preferred Name | Anti-CD20 Monoclonal Antibody TL011 |
| Definitions |
A monoclonal antibody directed against human CD20 with potential antineoplastic activity. Anti-CD20 monoclonal antibody TL011 specifically binds to the B cell-specific cell surface antigen CD20 antigen (MS4A1; membrane-spanning 4-domains, subfamily A, member 1), thereby potentially triggering an immune response against CD20-positive B cells, leading to B cell apoptosis. CD20 is a non-glycosylated cell surface phosphoprotein that is exclusively expressed on B cells during most stages of B cell development and is often overexpressed in B-cell malignancies.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A monoclonal antibody directed against human CD20 with potential antineoplastic activity. Anti-CD20 monoclonal antibody TL011 specifically binds to the B cell-specific cell surface antigen CD20 antigen (MS4A1; membrane-spanning 4-domains, subfamily A, member 1), thereby potentially triggering an immune response against CD20-positive B cells, leading to B cell apoptosis. CD20 is a non-glycosylated cell surface phosphoprotein that is exclusively expressed on B cells during most stages of B cell development and is often overexpressed in B-cell malignancies. |
|---|---|
| prefLabel | Anti-CD20 Monoclonal Antibody TL011
|
| label | Anti-CD20 Monoclonal Antibody TL011
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| NCI_META_CUI | CL426019
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| PDQ_Closed_Trial_Search_ID | 686495
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| code | C94206
|
| prefixIRI | NCIT:C94206
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| in_subset | |
| Preferred_Name | Anti-CD20 Monoclonal Antibody TL011
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| Maps_To | Anti-CD20 Monoclonal Antibody TL011
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| NCI_Drug_Dictionary_ID | 686495
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 686495
|
| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
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