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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C942
http://purl.obolibrary.org/obo/NCIT_C942
|
|---|---|
| Preferred Name | Vitamin E Compound |
| Definitions |
A natural fat-soluble antioxidant with potential chemopreventive activity. Also known as tocopherol, vitamin E ameliorates free-radical damage to biological membranes, protecting polyunsaturated fatty acids (PUFA) within membrane phospholipids and within circulating lipoproteins. Peroxyl radicals react 1000-fold faster with vitamin E than with PUFA. In the case of oxygen free radical-mediated tumorigenesis, vitamin E may be chemopreventive. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A natural fat-soluble antioxidant with potential chemopreventive activity. Also known as tocopherol, vitamin E ameliorates free-radical damage to biological membranes, protecting polyunsaturated fatty acids (PUFA) within membrane phospholipids and within circulating lipoproteins. Peroxyl radicals react 1000-fold faster with vitamin E than with PUFA. In the case of oxygen free radical-mediated tumorigenesis, vitamin E may be chemopreventive. (NCI04) |
|---|---|
| prefLabel | Vitamin E Compound
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| label | Vitamin E Compound
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| CHEBI_ID | CHEBI:33234
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| PDQ_Closed_Trial_Search_ID | 38321
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| code | C942
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| Unit | mg
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| prefixIRI | NCIT:C942
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| in_subset |
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| Display_Name | Vitamin E Compound
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| Preferred_Name | Vitamin E Compound
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| Tolerable_Level | Y
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| Nutrient | Y
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| Contributing_Source |
CRCH
CTRP
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| Maps_To | Vitamin E Compound
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| CAS_Registry | 1406-18-4
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| Micronutrient | Y
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| NSC Number | 20812
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| NCI_Drug_Dictionary_ID | 38321
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| Legacy Concept Name | Vitamin_E
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| US_Recommended_Intake | Y
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| type | |
| ALT_DEFINITION | A nutrient that the body needs in small amounts to function and stay healthy. Vitamin E helps prevent cell damage caused by free radicals (highly reactive chemicals). It is fat-soluble (can dissolve in fats and oils) and is found in seeds, nuts, leafy vegetables, and vegetable oils. Not enough vitamin E can result in infertility (the inability to produce children). It is being studied in the prevention and treatment of some types of cancer. Vitamin E is a type of antioxidant.
A fat-soluble vitamin which is primarily a chain-breaking antioxidant that prevents the propagation of lipid peroxidation.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 38321
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| Accepted_Therapeutic_Use_For | Vitamin E deficiency
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| Semantic_Type |
Pharmacologic Substance
Vitamin
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| UMLS_CUI | C0042874
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