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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Id | http://purl.obolibrary.org/obo/NCIT_C939
http://purl.obolibrary.org/obo/NCIT_C939
|
|---|---|
| Preferred Name | Cobalamin |
| Definitions |
An essential nutrient and natural water-soluble vitamin of the B-complex family that must combine with an intrinsic factor for absorption by the intestine, Vitamin B12 (cyanocobalamin) is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An essential nutrient and natural water-soluble vitamin of the B-complex family that must combine with an intrinsic factor for absorption by the intestine, Vitamin B12 (cyanocobalamin) is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions. |
|---|---|
| label |
Cobalamin
|
| prefLabel |
Cobalamin
|
| Legacy Concept Name |
Vitamin_B12
|
| in_subset | |
| Unit |
mcg
|
| Preferred_Name |
Cobalamin
|
| Chemical_Formula |
C62H88N13O14P.Co
|
| Display_Name |
Cobalamin
|
| USDA_ID |
481
|
| PDQ_Open_Trial_Search_ID |
530928
|
| UMLS_CUI |
C0042845
|
| FDA_UNII_Code |
8406EY2OQA
|
| prefixIRI |
NCIT:C939
|
| Nutrient |
Y
|
| NCI_Drug_Dictionary_ID |
530928
|
| INFOODS |
VITAB12
|
| Contributing_Source |
CRCH
CTRP
FDA
|
| subClassOf | |
| CHEBI_ID |
CHEBI:30411
CHEBI:28911
|
| Micronutrient |
Y
|
| code |
C939
|
| type | |
| ALT_DEFINITION |
A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Vitamin B12 helps make red blood cells, DNA, RNA, energy, and tissues, and keeps nerve cells healthy. It is found in liver, meat, eggs, poultry, shellfish, milk, and milk products. Vitamin B12 is water-soluble (can dissolve in water) and must be taken in every day. Not enough vitamin B12 can cause certain types of anemia (a condition in which the number of red blood cells is below normal) and neurologic disorders. It is being studied with folate in the prevention and treatment of some types of cancer.
Cobalt-containing water soluble vitamin that is a coenzyme in the metabolism of fatty acids of odd-chain length and in methyl transfer. (DRI)
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| PDQ_Closed_Trial_Search_ID |
530928
|
| Semantic_Type |
Pharmacologic Substance
Vitamin
|
| CAS_Registry |
13408-78-1
|
| US_Recommended_Intake |
Y
|
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