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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C935
http://purl.obolibrary.org/obo/NCIT_C935
|
|---|---|
| Preferred Name | Vindesine Sulfate |
| Definitions |
The sulfate salt form of Vindesine. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The sulfate salt form of Vindesine. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI) |
|---|---|
| prefLabel | Vindesine Sulfate
|
| label | Vindesine Sulfate
|
| CHEBI_ID | CHEBI:32295
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| PDQ_Closed_Trial_Search_ID | 39732
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| code | C935
|
| prefixIRI | NCIT:C935
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| in_subset | |
| Preferred_Name | Vindesine Sulfate
|
| FDA_UNII_Code | CPH2U7DNDY
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| Contributing_Source | FDA
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| Chemical_Formula | C43H55N5O7.H2O4S
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| CAS_Registry | 59917-39-4
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| NSC Number | 245467
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| NCI_Drug_Dictionary_ID | 39732
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| Legacy Concept Name | Vindesine_Sulfate
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| Has_Free_Acid_Or_Base_Form | |
| type | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39732
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0042683
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| Delete | Subject | Author | Type | Created |
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