loading...| Preferred Name |
Vinblastine Sulfate |
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| Synonyms |
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| Definitions |
The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthus roseus (Madagascar periwinkle) with antineoplastic properties. Vinblastine disrupts microtubule formation and function during mitosis and interferes with glutamic acid metabolism. (NCI04) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C931 |
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| ALT_DEFINITION |
A drug used with other drugs to treat several types of cancer, including advanced Hodgkin lymphoma and advanced testicular germinal-cell cancers. It is also being studied in the treatment of other types of cancer. Velban comes from the periwinkle plant Vinca rosea Linn. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of vinca alkaloid and a type of antimitotic agent. |
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| CAS_Registry |
143-67-9 |
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| CHEBI_ID |
CHEBI:9984 |
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| Chemical_Formula |
C46H58N4O9.H2O4S |
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| code |
C931 |
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| Contributing_Source |
CTRP FDA |
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| definition |
The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthus roseus (Madagascar periwinkle) with antineoplastic properties. Vinblastine disrupts microtubule formation and function during mitosis and interferes with glutamic acid metabolism. (NCI04) |
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| Display_Name |
Vinblastine Sulfate |
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| FDA_UNII_Code |
N00W22YO2B |
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| Has_Free_Acid_Or_Base_Form | ||
| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Vinblastine Sulfate |
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| Legacy Concept Name |
Vinblastine_Sulfate |
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| Maps_To |
Vinblastine Sulfate |
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| NCI_Drug_Dictionary_ID |
688303 |
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| NSC Number |
49842 |
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| PDQ_Closed_Trial_Search_ID |
688303 |
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| PDQ_Open_Trial_Search_ID |
688303 |
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| Preferred_Name |
Vinblastine Sulfate |
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| prefixIRI |
NCIT:C931 |
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| prefLabel |
Vinblastine Sulfate |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0042671 |
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| subClassOf |