Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C931
http://purl.obolibrary.org/obo/NCIT_C931
Preferred Name

Vinblastine Sulfate
Definitions
The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthus roseus (Madagascar periwinkle) with antineoplastic properties. Vinblastine disrupts microtubule formation and function during mitosis and interferes with glutamic acid metabolism. (NCI04)
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthus roseus (Madagascar periwinkle) with antineoplastic properties. Vinblastine disrupts microtubule formation and function during mitosis and interferes with glutamic acid metabolism. (NCI04)
prefLabel
Vinblastine Sulfate
label
Vinblastine Sulfate
CHEBI_ID
CHEBI:9984
PDQ_Closed_Trial_Search_ID
688303
code
C931
Has_Target
prefixIRI
NCIT:C931
in_subset
Display_Name
Vinblastine Sulfate
Preferred_Name
Vinblastine Sulfate
FDA_UNII_Code
N00W22YO2B
Contributing_Source
CTRP
FDA
Chemical_Formula
C46H58N4O9.H2O4S
Maps_To
Vinblastine Sulfate
CAS_Registry
143-67-9
NSC Number
49842
NCI_Drug_Dictionary_ID
688303
Legacy Concept Name
Vinblastine_Sulfate
Has_Free_Acid_Or_Base_Form
type
ALT_DEFINITION
A drug used with other drugs to treat several types of cancer, including advanced Hodgkin lymphoma and advanced testicular germinal-cell cancers. It is also being studied in the treatment of other types of cancer. Velban comes from the periwinkle plant Vinca rosea Linn. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of vinca alkaloid and a type of antimitotic agent.
Is_Value_For_GDC_Property
subClassOf
PDQ_Open_Trial_Search_ID
688303
Semantic_Type
Organic Chemical
Pharmacologic Substance
UMLS_CUI
C0042671
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